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Tofacitinib, a JAK inhibitor, improved hair regrowth in most patients with severe alopecia areata and had minimal side effects.

New treatments for hair loss are being developed using molecular biology.

Lipid nanoparticles improve drug delivery through the skin, offering stability, controlled release, and better compatibility with skin.

Only minoxidil and finasteride are FDA-approved for hair loss, with other treatments available but less effective or with side effects.

Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.

Tofacitinib effectively reduced hair loss in alopecia areata patients without adverse effects.

New drugs targeting the JAK-STAT pathway show promise for treating inflammatory skin diseases.

Exosomes show promise for tissue repair and regeneration with advantages over traditional cell therapies.

Busulfan/cyclophosphamide and total bone irradiation are equally effective for AML transplants.

Topical Vorinostat shows promise for treating alopecia areata by promoting hair regrowth.

The model and estimator can predict drug exposure in kidney transplant patients well.

The document lists various dermatology topics, treatments, and diagnostic methods.

γδ T cells help with hair growth during wound healing in mice.

Prunus Tomentosa extract is effective in promoting hair growth, similar to minoxidil.

The document concluded that FDA-approved treatments like minoxidil and finasteride are effective for hair loss, while the effectiveness of natural remedies and other non-approved treatments is not well-supported by evidence.

Finasteride's sexual side effects not caused by androgen deficiency or SRD5A inhibition.

Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

Ruxolitinib effectively regrows hair in most patients with severe hair loss.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Researchers created human hair follicles using a new method that could help treat hair loss.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.

Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.