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DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.

Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.

Cannabinoids may help treat various skin conditions.

Creating fully functional artificial skin for chronic wounds is still very challenging.

The right cells and signals can potentially lead to scarless wound healing, with a mix of natural and external wound healing controllers possibly being the best way to achieve this.

Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.

Minoxidil and Finasteride are effective for male baldness; more research is needed for hair aging treatments.

TRPV3 in skin cells causes inflammation and cell death.

Stress might contribute to hair loss in alopecia areata.

Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

Janus kinase inhibitors show promise in treating alopecia areata but need better topical formulations.

The project created a standardized system for classifying skin lesions in lab rats and mice.

New treatments for COVID-19 show promise, but more effective antiviral drugs are needed.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.

Significant progress was made in understanding PXE, but effective treatments are still needed.

The study concluded that immune cells attacking hair follicles cause hair loss in alopecia, with genetics and environment also playing a role, and highlighted the potential of certain treatments.

Proxalutamide significantly lowered hospital admissions for male COVID-19 patients compared to a placebo.

Teriflunomide effectively reduces relapse rates and disease progression in multiple sclerosis but is not safe for use during pregnancy.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.

3D bioprinting improves wound healing by precisely creating scaffolds with living cells and biomaterials, but faces challenges like resolution and speed.

Notch signaling disruptions can cause various skin diseases.

Platelet-derived bio-products help in wound healing and tissue regeneration but lack standardized methods, and their use in medicine is growing.

Stopping mitochondrial respiration can prevent brain cancer spread in skin cancer patients, and plant compound β-sitosterol could help achieve this.

Disrupting the Flcn gene in mice causes early kidney cysts and tumors, which can be treated with rapamycin.

Auto-antibody testing is a useful but not definitive tool in diagnosing interstitial lung diseases, and using a specific algorithm could make testing more cost-effective.

Neuroactive steroids and the enzyme 5α-reductase might be involved in the development of Tourette's syndrome.