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This article reviews organotypic skin culture systems and their applications in dermatological research, highlighting their ability to model human epidermal conditions in vitro, but it reports no new clinical results.

This study highlights that hair-bearing organoids derived from embryonic stem cells can effectively model androgenic alopecia conditions and test the efficacy of anti-hair loss treatments.

This review discusses the potential benefits of phytochemicals for hair care and emphasizes the need for more robust preclinical and clinical studies, without reporting new clinical results.

This narrative review found that post-COVID-19 hair loss, particularly telogen effluvium, poses a significant mental and social burden, with minoxidil potentially aiding recovery, although more clinical research is needed to confirm its effectiveness.

This study reviews the potential of rosemary for hair loss treatment, highlighting its beneficial bioactive compounds that may support healthier scalps and promote hair growth, though inconsistencies in formulations and lack of long-term safety data suggest more research is needed.

This review highlights advancements in nanotechnology-based treatments for androgenetic alopecia, noting that these strategies could improve targeting and modulation of hair follicle environments compared to traditional therapies like minoxidil and finasteride, but also emphasizes challenges around safety, manufacturing, and regulation.

This review examined 40 studies on exosome-based therapies for alopecia areata, reporting significant hair regrowth and improvements in hair count, length, and thickness, but highlighted the need for standardized methodologies and robust RCTs before clinical application.

In this narrative review, researchers synthesized current evidence on topical metformin's potential benefits for various skin conditions, citing primarily preclinical studies that highlight its anti-inflammatory, antioxidant, and regenerative properties, although clinical translation requires further rigorous trials.

This review discusses the therapeutic potential of costunolide for various diseases, highlighting its bioactivity and mechanisms, but it reports no new experimental results.

This research observed that EGFR activity appears to maintain hair follicle quiescence and immune privilege, and its inhibition may lead to stem cell apoptosis and scarring alopecia during inflammation.

This source reviews the potential of polyphenols as therapeutic and preventive treatments for common skin disorders such as acne, fungal infections, dermatitis, alopecia, and skin cancer, emphasizing their anti-inflammatory and antimicrobial effects and ability to penetrate the skin barrier.

This review discusses the role of PPARs in skin health, suggesting both potential benefits and adverse effects, but reports no new experimental results; the authors emphasize the need for more research to understand these pathways.

This review suggests that mesenchymal stem cells' therapeutic effects might be due to bioactive substances they release, rather than the cells themselves, highlighting the potential of the MSC secretome as a novel, cell-free therapeutic approach.

This review assesses the potential of ginger, garlic, onion, and clove as complementary herbal treatments for hair and scalp health, reporting that onion juice shows the strongest clinical evidence for hair regrowth, particularly in alopecia areata, while garlic exhibits promising preclinical regenerative effects.

Minoxidil solution and foam both increase hair growth, but the solution works better than the foam.

This review explores the immunopharmacological potential of A. lappa for inflammatory musculoskeletal disorders (IMSDs) but reports no new clinical results, emphasizing the need for standardized research methodologies.

This review evaluates herbal botanicals like onion, garlic, ginger, and clove for hair and scalp health, noting that onion juice shows the strongest clinical evidence for hair regrowth particularly in alopecia areata, although these cannot replace traditional medical treatments.

In this clinical study, researchers observed that a shampoo formulated with Inula helenium and Caesalpinia Sappan extracts significantly increased total hair count after 16 and 24 weeks in patients with androgenetic alopecia, suggesting it may help prevent hair loss and promote hair growth.

This review discusses the potential role of Garudan kizhangu ennai, a polyherbal Siddha formulation, in managing alopecia areata and highlights its various pharmacological properties, although further clinical studies are needed to confirm its efficacy.

This review discusses the antiviral potential of cepharanthine against SARS-CoV-2, noting its effectiveness in preclinical models but presenting no new clinical results.

This review discusses the impact of chemotherapy-induced alopecia on cancer patients, the current use of scalp cooling for prevention, and potential future treatments, but presents no new clinical results.

This review discusses current challenges in selective androgen receptor modulator discovery and preclinical evaluation and reports no new results, emphasizing the need for basic research to improve safety and selectivity.

This review summarizes preclinical and clinical information on herbal products for hair loss treatment, highlighting their mechanisms, follicular penetration, and potential side effects, suggesting they may offer alternatives to synthetic drugs with fewer side effects.

This review discusses the development and rapid approval of COVID-19 vaccines and notes the observation of autoimmune disorders, such as alopecia areata, following vaccination; it provides no new clinical results.

This review discusses the molecular mechanisms of androgen action in human hair follicles and reports no new findings; the authors emphasize the need for further research to improve treatments for hair disorders.

The new chemotherapy combination for advanced lung cancer showed a 35.7% response rate but caused significant side effects.

This review highlights that herbal hair oils, incorporating medicinal plant extracts and carrier oils, show promise in promoting hair growth and scalp health by demonstrating antioxidant, anti-inflammatory, and antimicrobial properties, with clinical evidence supporting reductions in hair fall and dandruff with minimal side effects.

This review discusses the synthesis and biological activities of jasmonates, highlighting their potential as drugs and prodrugs, but reports no new clinical results; further research and trials are anticipated.

This study found that a new formulation kit of Pielus Anti-hair loss lotion and shampoo, used daily for 90 days, was safe and effective in reducing hair loss and increasing hair strength and density among patients with telogen effluvium and/or androgenetic alopecia.

This article reviews the use of various treatments for alopecia and their potential impact on COVID-19 outcomes, emphasizing the importance of patient registries in generating real-world evidence; it reports no new results.