Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this case report from People's College of Medical Sciences, a 20-year-old man initially misdiagnosed with Addison's disease was ultimately found to have strongyloidiasis, with his symptoms and weight loss improving after antihelminthic treatment.

This study reports that human eccrine sweat gland cells are capable of forming a stratified epidermis, suggesting they may serve as an additional source of keratinocytes for skin repair.

This review discusses the evolution and development of smart and multifunctional microneedles, highlighting their potential future importance in medical applications, but it reports no new experimental results.

This review covers the molecular basis of Birt–Hogg–Dubé syndrome and its implications for potential therapeutic targets, but it does not report new experimental results.

This review discusses the potential of topical nanoemulsions to transform skin cancer treatment by improving drug delivery and minimizing side effects, highlighting their advantages like enhanced skin permeation and controlled release, despite existing challenges.

This study reported that heat treatment significantly increased the incidence of alopecia areata in C3H/HeJ mice, suggesting a role for induced HSPA1A/B expression in disease development.

This review discusses the pharmacological actions and potential therapeutic benefits of ginsenoside compound K for metabolic disorders, reports no new clinical results, and suggests further research on its bioavailability and toxicity.

This review emphasized the significance of biliary fibrosis in hepatobiliary disorders, exploring its clinical manifestations, epidemiology, and cellular factors, and provided insights into current clinical trials and strategies for managing fibrosis-related cholangiopathies.

This review introduces a framework to integrate bioinspired conductive materials and advanced 3D/4D printing in regenerative medicine for dynamic, responsive tissue regeneration, emphasizing the potential of smart scaffolds to adapt to physiological cues.

In this review, the authors describe how glucose metabolism supports various stages of wound healing by providing energy and necessary substances, noting that abnormal glucose metabolism in chronic wounds increases oxidative stress and inflammation, significantly hindering healing.

This review discusses the pharmacology and potential therapeutic effects of rare ginsenoside compound K on metabolic disorders but presents no new clinical results, highlighting the need for further studies on its bioavailability and toxicity.

This review suggests that hyperspectral and terahertz imaging show promise in non-invasively assessing scalp changes associated with hair loss, but further validation is needed for clinical application.

This review examines current understanding of how skin microbiota interact with and influence wound healing, highlighting the roles of commensal microorganisms in inflammation resolution, tissue regeneration, and barrier restoration, and discusses potential microbiota-based therapies for improving wound management.

In this study, the researchers identified MJ04, a selective JAK3 inhibitor, as a promising candidate for promoting hair growth, demonstrating efficacy in both animal models and human hair follicle assays with a favorable safety and pharmacokinetic profile.

In this rodent model study, the researchers reported that using low-intensity focused ultrasound with phenytoin enhanced its anti-epileptic efficacy by disrupting plasma protein binding in a region-specific manner, reducing seizure frequency and duration.

This review discusses the complexity of identifying hair follicle antigens involved in alopecia areata and reports no new clinical results, emphasizing the need for further research on autoantigen identity.

This study found that adult mouse dermis can be reprogrammed by epidermal cues to resemble neonatal dermis, with changes in fibroblast proliferation and extracellular matrix composition.

This narrative review highlights the crucial role of micronutrients and gut microbiota in thyroid function and suggests that nutritional imbalances may contribute to thyroid dysfunction or diseases.

This review discusses the phytochemistry and pharmacological activities of Perilla frutescens, detailing its bioactive compounds and their potential health benefits, but reports no new clinical results.

This study found that pulmonary delivery of cepharanthine significantly improved bioavailability and may provide protective effects against pulmonary fibrosis related to COVID-19 infection in a rat model.

This review highlights the challenges in developing nano-scale drug delivery systems for natural antioxidants in wound healing, pointing out issues like low solubility and skin permeability, and discusses potential solutions such as combining polymers and lipids to enhance delivery effectiveness.

This review highlights the potential of nanotechnology-based formulations in hair care and treatment, emphasizing how these innovative materials can enhance the stability, efficacy, and safety of active compounds while addressing the limitations of conventional formulations.

This review discusses Amphiregulin (AREG) as a potential target for treating fibrotic disorders and cancer, highlighting its role in disease progression and promising results in preclinical studies and early trials.

This study found that spanlastic gel loaded with thymoquinone and ascorbic acid improved skin deposition and tyrosinase inhibition, suggesting potential as a treatment for hyperpigmentation.

This study comparatively evaluated different extraction techniques for Schinus terebinthifolius Raddi leaf extracts and found that conventional extraction with ethanol yielded the highest antioxidant activity and beneficial effects on skin cell viability, supporting its potential use in sustainable cosmeceutical formulations targeting skin aging.

This perspective study suggests that plant-derived extracellular vesicles could advance the use of Ayurvedic medicinal plants in nanomedicine by enhancing their therapeutic potential and guiding future research.

This study found that dietary vitamin E influenced gene expression in rat livers, altering genes related to metabolism, coagulation, and steroid processing, and confirmed its effects on related biological endpoints.

This review discusses current clinical trials targeting Wnt signaling in gastrointestinal cancers and reports no new results; the authors highlight challenges and consider alternative strategies for cancer treatment.

This review discusses the increasing demand for facial hair transplantation in hair restoration, noting its benefits and the natural-appearing results achieved through modern techniques, but it reports no new clinical results.

The document concludes that choosing the right forehead and brow lifting technique based on individual patient characteristics is crucial to prevent complications and achieve desired results.