research Small Cell Lung Cancer: Results of a Phase II Study of 1,2,4-Triglycidylurazol
The drug TGU was ineffective against small cell lung cancer and caused significant bone marrow suppression.
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research PLCD1 and Pilar Cysts
The research linked PLCD1 gene variants to the development of trichilemmal cysts.
research Androgenetic Alopecia, Trichotrophic Substances, and Histologic Studies of the Human Scalp
Minoxidil promotes hair growth but exact mechanism is unknown.
research Effect of a Combination of Ethinylestradiol and Desogestrel in Adolescents with Oligomenorrhea and Ovarian Hyperandrogenism
The study involved 9 oligomenorrheic adolescent girls with ovarian hyperandrogenism and 8 eumenorrheic controls, treated with a monophasic oral contraceptive containing 0.03 mg ethinylestradiol and 0.150 mg desogestrel for 6 months. The treatment reduced levels of LH, FSH, androstenedione, testosterone, and DHEA-S, while increasing SHBG in both groups. In oligomenorrheic girls, it also decreased ovarian volume and cystic follicles. However, most hormonal levels returned to pre-treatment values 3 months after stopping the treatment, except for SHBG and ovarian volume. Six oligomenorrheic girls reported improved skin and reduced hair growth. Despite its temporary effects, the treatment was effective in managing hyperandrogenism and may help prevent adult micropolycystic ovarian disease.
research Plant Saponin Biosurfactants Used as Soap, Hair Cleanser, and Detergent in India
Plant saponins from Indian plants are natural, cost-effective, and safe for use in soaps, detergents, and hair care products.
research Microneedle Transdermal Drug Delivery Systems for Allergen-Specific Immunotherapy, Skin Disease Treatment, and Vaccine Development
Microneedles are a promising method for drug delivery, offering efficient and convenient alternatives with fewer side effects.
research Telogen Effluvium in the New SARS-CoV-2 Era
COVID-19 and related stress may increase hair loss known as Telogen effluvium.
research Aesthetic Facial Plastic Surgery: A Multidisciplinary Approach
The book showed that combining expertise from various specialties improves facial cosmetic surgery outcomes.
research Current Status of the Applications of Conditioned Media Derived from Mesenchymal Stem Cells for Regenerative Medicine
Conditioned media from mesenchymal stem cells show promise for tissue repair and disease treatment, but more research is needed on their safety and effectiveness.
research New-Onset and Exacerbated Skin Diseases After COVID-19 Infection: A Systematic Review
COVID-19 infection can cause new hair loss conditions or worsen existing skin diseases, with hair loss being the most common issue.
research Current Stem Cell Technologies Used in Medicine
Stem cell technologies are mostly effective in treating diseases and repairing tissues.
research Comment on: The Gabrin Sign
The document suggests that more research is needed to confirm if baldness can indicate a higher risk of severe COVID-19 in men.
research Autistic-Undisciplined Thinking in the Practice of Medical Trichology
The article concludes that treating hair loss requires careful research, understanding the causes, and personalized treatment plans.
research The Beauty of Soy for Skin, Hair, and Nails
Soy can improve skin, hair, and nails.
research Volume Changes During Water Binding to Hair Fibers
Hair increases in size when it absorbs water, and treatments like bleaching affect how much water it can take in.
research Cardiovascular Safety and Benefits of Testosterone Implant Therapy in Postmenopausal Women: Where Are We?
Testosterone therapy for postmenopausal women appears safe and may protect against heart disease, but requires constant monitoring and more research for long-term effects.
research Effect of COVID-19 on Hair Diseases Observed by Health Care Providers: Analysis of 513 Participants
COVID-19 diagnosis is linked to new or worsening hair diseases, with stress from the pandemic likely contributing.
research The Psychological Impact of Aesthetic Surgery: A Mini-Review
Aesthetic surgery can worsen depression and anxiety, especially in those with existing mood issues.
research Moxibustion Improves Ovarian Function Based on the Regulation of the Androgen Balance
Moxibustion may help improve ovarian function by changing androgen levels.
research The COVID-19 Pandemic and Its Skin Effects
COVID-19 can cause rashes and worsen existing skin conditions, and behaviors like frequent hand-washing can lead to hand dermatitis.
research Differential Gene Expression in Post-Finasteride Syndrome Patients
Gene expression differences in PFS patients suggest a potential organic cause for symptoms.
research Response to Effectiveness of Dutasteride in a Large Series of Patients with Frontal Fibrosing Alopecia in Real Clinical Practice
The authors suggest that 5-α-reductase inhibitors, like dutasteride, are effective in treating frontal fibrosing alopecia and should be the first-line treatment, with other options for severe cases. They also recommend further research on Janus kinase inhibitors.
research Temporal Peaks Restoration: A New Innovation
The technique effectively restores temporal peaks in hair transplants using different hair densities and angles in three zones.
research An Unusual Presentation of X-Linked Adrenoleukodystrophy
A man with X-ALD improved after treatment, highlighting the need to consider X-ALD in similar patients and test their relatives.
research Hirsutism Following the Use of Bimatoprost Eyedrops for Glaucoma
A woman got unwanted hair growth on her face from using bimatoprost eyedrops for glaucoma.
research Should Finasteride Be Routinely Given Preoperatively for TURP?
Finasteride may reduce bleeding after TURP, but more research needed.
research In Vitro Culture Methods of Skin Cells for Optimal Skin Reconstruction by Tissue Engineering
New methods for growing skin cells can improve skin grafts by building blood vessels within them.
research An Overview of Female Pattern Hair Loss
Female pattern hair loss involves thinning hair on crown and frontal scalp, diagnosed by hair ratio, and treated with minoxidil, antiandrogens, or hair transplantation.
research Treatment Advances for Acne Vulgaris: The Scientific Role of Cannabinoids
Cannabidiol shows promise as an effective treatment for acne.
research The Multisystem Impact of Long COVID: A Comprehensive Review
Long COVID affects many body systems and needs careful management.