research Controversies Regarding Transdermal Androgen Therapy in Postmenopausal Women
Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.
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research Inhibition of Mitochondrial Respiration Prevents BRAF-Mutant Melanoma Brain Metastasis
Stopping mitochondrial respiration can prevent brain cancer spread in skin cancer patients, and plant compound β-sitosterol could help achieve this.
research The Eyelash Follicle Features and Anomalies: A Review
Eyelashes protect the eyes, but more research is needed to understand how.
research Pregnancy and Skin: Changes and Dermatoses
Most skin changes during pregnancy are harmless and temporary, but some can risk the fetus and need careful treatment.
research Expanding Clinical Indications of Mechanically Isolated Stromal Vascular Fraction: A Systematic Review
The regenerative solution, tSVF, is a safe and effective treatment for various conditions like aged skin, scars, wounds, and more, but more research is needed to find the best way to use it.
research Cutaneous Toxicities of New Treatments for Melanoma
New melanoma treatments can cause skin side effects, including skin cancer and rashes, but combining treatments may reduce these risks.
research LncRNA PlncRNA-1 Regulates Proliferation and Differentiation of Hair Follicle Stem Cells Through TGF-β1-Mediated Wnt/β-Catenin Signal Pathway
PlncRNA-1 helps hair follicle stem cells grow and develop by controlling a specific cell signaling pathway.
research Psychodermatology: The Intersection of Dermatology and Psychiatry
Many skin patients also have mental health issues, and doctors should treat both together.
research Testosterone Levels in Relation to Oral Contraceptive Use and the Androgen Receptor CAG and GGC Length Polymorphisms in Healthy Young Women
Oral contraceptives lower testosterone levels in women, especially those with certain genetic traits, and may be linked to increased breast cancer risk.
research Steroid Sulfatase Inhibitors: Therapeutic Applications and Development
Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.
research Toxic Epidermal Necrolysis
Toxic Epidermal Necrolysis is a rare, serious skin condition that can affect anyone, is more common in women, and may be linked to genetics, with a 20% mortality rate mainly due to sepsis.
research The Genetics of Human Skin Disease
Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.
research Drug Repositioning Using In Silico Compound Profiling
Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.
research The Immunological Impact of IL-1 Family Cytokines on the Epidermal Barrier
IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.
research The Value of Trichoscopy in the Differential Diagnosis of Scalp Lesions in Pemphigus Vulgaris and Pemphigus Foliaceus
Trichoscopy helps tell apart scalp lesions in pemphigus vulgaris and pemphigus foliaceus and is useful for choosing biopsy locations.
research Activation of Androgen Receptor Sensitizes Breast Carcinomas to NVP-BEZ235's Therapeutic Effect Mediated by PTEN and KLLN Upregulation
Breast cancer treatments work better with AR activation, improving results and reducing side effects.
research Overview of Ultrasound Imaging Applications in Dermatology
Ultrasound is a useful, non-invasive tool in dermatology for diagnosing skin conditions and guiding treatments, but it has some limitations.
research Binding Interactions of Keratin-Based Hair Fiber Extract to Gold, Keratin, and BMP-2
Keratin from hair binds well to gold and BMP-2, useful for bone repair.
research Retinoid Metabolism Is Altered in Human and Mouse Cicatricial Alopecia
Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.
research Optimizing Psychological Interventions for Trichotillomania: An Update on Current Empirical Status
Cognitive-behavioral therapy is the best treatment for hair-pulling disorder, and combining it with other therapies could improve results.
research Immunization by Application of DNA Vaccine onto a Skin Area Where the Hair Follicles Have Been Induced into Anagen-Onset Stage
Applying a DNA vaccine to skin with active hair growth boosts immune response and protection against anthrax in mice.
research Hydroxysteroid Dehydrogenase (17β-HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors: Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels
Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.
research Platelet-Rich Plasma: Principles and Applications in Plastic Surgery
Platelet-rich plasma is beneficial in various plastic surgery applications, but more research is needed to standardize its use.
research Commonalities Between COVID-19 and Radiation Injury
Some drugs may help treat both COVID-19 and radiation injury.
research Dietary Vitamin A Regulates Wingless-Related MMTV Integration Site Signaling to Alter the Hair Cycle
Eating vitamin A affects hair growth and health by changing cell signals in mice.
research Alterations of Gut Microbiota Composition in Post-Finasteride Patients: A Pilot Study
Post-finasteride patients show changes in gut bacteria, possibly causing various symptoms.
research Hair Tourniquet Syndrome of the Toe: Report of Two New Cases
Two babies needed surgery to remove hair tightly wrapped around their toes to prevent serious injury.
research The Role of Leptin in Selected Skin Diseases
Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.
research Establishment of Keratinocyte Cell Lines from Human Hair Follicles
Scientists created keratinocyte cell lines from human hair that can differentiate similarly to normal skin cells, offering a new way to study skin biology and diseases.
research Adverse Sexual Effects of Treatment with Finasteride or Dutasteride for Male Androgenetic Alopecia: A Systematic Review and Meta-Analysis
Finasteride and dutasteride increase sexual dysfunction risk by 1.57 times in male hair loss treatment.