Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study reported that women with polycystic ovarian syndrome have higher serum irisin levels, which are associated with metabolic and hormonal imbalances, including hyperandrogenism, total cholesterol, and visceral fat.

In this review, researchers explored the multifaceted role of NF-κB signaling in various biological processes and diseases, including its interactions with other pathways, and discussed possible therapeutic approaches targeting this pathway for treating conditions like cancer, autoimmune disorders, and COVID-19.

In this study, researchers identified several active metabolites in Eclipta alba, demonstrated strong interaction with Alzheimer's disease proteins, and found that 28 days of treatment improved memory without significant toxicity in rats, suggesting potential pathways for treating Alzheimer's.

This study observed that pantethine, a vitamin B5 precursor, attenuates tumor growth in immunocompetent mice by enhancing antitumor immunity, but its effect is limited by immune cell exhaustion over time.

In this study, researchers found that most patients with frontal fibrosing alopecia lacked the protective rs1800440 polymorphism in the CYP1B1 gene, suggesting its potential role in the development of this condition, while a significant number carried the rs9258883 polymorphism in HLA-B*07:02.

This study created a detailed spatial atlas of healthy human skin and basal cell carcinoma, revealing a potential hair follicle origin for basal cell carcinoma and expansion of certain mesenchymal cell populations.

This study explored the molecular biology of skin adaptations in pangolins, revealing that certain genes for lipid synthesis have inactive patterns, while others related to skin function remain intact, suggesting complex evolutionary changes in their skin physiology.

This study investigated pangolin skin genetics, finding that while sweat gland-related genes are not inactivated, several genes related to sebaceous gland function are, which highlights complex evolutionary adaptations in mammalian skin.

This study found differences in melanin content and gene expression in skin under black and white hair of giant pandas, providing a basis for further research on hair color distribution and skin diseases.

This study found that SMAD2 overexpression in human hair follicle stem cells promoted differentiation and apoptosis while inhibiting proliferation, and Smurf2 upregulation limited mouse wound healing by suppressing the SMAD2/NANOG/DNMT1 axis.

This review examines the relationship between glycation, insulin resistance, and PCOS, discussing various treatments and highlighting M. oleifera and S. platensis as potential therapeutic agents, but reports no new clinical results.

This study found that the rs1128977 SNP in the RXRG gene may be linked to altered clinical characteristics such as higher HDL-cholesterol levels and increased body mass index in individuals with dyslipidemia.

This review discusses the role of metabolism in maintaining adult stem cell homeostasis with aging and highlights the potential benefits of dietary restrictions on stem cell function and longevity. It reports no new clinical results and emphasizes the need for further molecular studies.

This study found that metabolic syndrome was more prevalent among androgenetic alopecia patients than controls, with higher serum RANTES levels suggesting a potential role in the syndrome's pathogenesis.

This study observed that five cases of primary cicatricial alopecia showed an excellent response to a combination of oral zinc and long-pulsed Nd:YAG 1064-nm laser treatment, suggesting this approach may be beneficial for certain types of this condition.

This study found that Ift20 is essential for hair follicle stem cell identity and hair regrowth, and it regulates keratinocyte migration during wound healing through focal adhesion integrin recycling, independently of ciliogenesis.

This review examines the use of natural remedies, including various herbs, for treating polycystic ovary syndrome, but reports no new clinical results.

This study found that a combination of azelaic acid, minoxidil, and caffeine significantly reduced skin flap necrosis in rats, likely by increasing nitric oxide content and iNOS expression, compared to individual treatments.

This study evaluated the antifungal activity of lemongrass oil in anti-dandruff gel shampoo formulations and found that a 10% lemongrass oil concentration was the most effective at inhibiting the growth of the dandruff-causing fungus Pityrosporum ovale.

This article reviews treatment approaches for cicatricial alopecia, describing how medication efficacy varies and suggesting autologous hair transplantation for stable cases; no new clinical data are presented.

PRP might help with hair growth and skin rejuvenation, but more research is needed to prove its effectiveness.

This review discusses the roles of DNA methylation in skin development and regeneration, highlighting its impact on embryonic skin lineage, homeostasis, and potential therapeutic targets, but reports no new clinical results.

This study is the first to report that apremilast may be effective in treating refractory lichen planopilaris and frontal fibrosing alopecia, though some patients experienced adverse effects leading to discontinuation.

This article reports no new data; it describes the role of sebum in influencing the skin microbiome and epithelial tissues and discusses its altered composition during transit through the sebaceous duct.

Men with a certain type of hair loss often use facial moisturizers, and a specific antibiotic treatment may help another hair condition.

Skin aging reflects overall body aging and can indicate internal health conditions.

This review discusses genetic and epigenetic studies of PCOS, highlighting Genome-Wide Association Studies that found genetic variants related to gonadotrophin secretion influencing PCOS susceptibility, but it reports no new findings.

This letter to the editor shares a case study of lentiginous melanoma that appears clinically malignant but histopathologically benign, involving the BRAFV600R mutation.

This case report highlights that women with nonclassical congenital adrenal hyperplasia should be aware of the risk of having a child with classical CAH if their partner also carries a severe mutation.

This review discusses factors affecting hair aging, such as inflammation and UV exposure, and examines potential anti-aging benefits of antioxidants and nutraceuticals for hair, but reports no new clinical results.