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Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Fat cells are important for tissue repair and stem cell support in various body parts.

The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.

Quercetin may help with PCOS symptoms, but more research is needed.

Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.

Some alternative treatments for hair loss might work, but more research is needed.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Plant-based ingredients are effective and safe for modern skincare products.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The document concludes that treating PCOS requires a combination of drugs to manage reproductive and metabolic symptoms, with more research needed on combination therapies.

Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.

Thymic transplantation normalized some T-cells but not others, maintaining immune function.

Curcumin may improve blood sugar levels and cholesterol in people with PCOS, but more research is needed.

Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.

Hedychium spicatum has medicinal properties but needs more research for scientific validation and use.

Continuous light exposure in rats leads to PCOS-like symptoms and suggests sleep habits might affect the disorder's development.

Finasteride can cause one-sided breast enlargement, which disappears after stopping the drug.

Longer hair loss leads to more severe CCCA; early treatment and avoiding damaging hairstyles help regrowth.

Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.

Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.

Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.

Safflower has been used in traditional medicine for centuries and shows promise in treating heart, brain, and inflammatory conditions, but more research is needed to ensure its safety.

PCOS is a complex disorder managed by treating symptoms and requires a team of specialists.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

Dying cells can help with faster healing and new hair growth by releasing a growth-promoting molecule.

Indigenous herbal medicines in the Indian subcontinent have potential for drug development but need more research and standardization.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.

The document concludes that understanding hair follicles requires more research using computational methods and an integrative approach, considering the current limitations in hair treatment products.