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Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

Topical spironolactone may help treat ocular graft-versus-host disease with minimal side effects.

Sebaceous glands are often preserved and PPARy expression is constant in some cases of Central Centrifugal Cicatricial Alopecia.

Certain genetic variants are linked to frontal fibrosing alopecia in Spanish patients.

Researchers found 15 new genetic links to skin traits in Japanese women.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Both human and animal-derived small extracellular vesicles speed up skin healing equally well.

Fat-related cells are important for initiating hair growth.

Licorice has many health benefits but should be used carefully due to possible side effects.

Hormones and signaling pathways control sebaceous gland function and could help treat acne.

A new botanical treatment improved hair growth and symptoms in lichen planopilaris patients.

Melandrium firmum extract helps mice grow hair by blocking a hair loss enzyme and changing hair growth genes.

PRP might help with hair growth and skin rejuvenation, but more research is needed to prove its effectiveness.

Excessive sun protection might cause frontal fibrosing alopecia by disrupting skin immune balance.

Pregnancy right after giving birth in mice lacking IL-10 causes milk that leads to liver issues and hair loss in their babies.

Azelaic acid helps protect hair cells from UV damage and encourages hair growth by increasing certain gene expressions and proteins.

Genes and epigenetic changes are important in the development of Polycystic Ovary Syndrome.

Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.

More high-quality research is needed to recommend flavonoids and saponins for clinical use.

Lung and liver macrophages protect our tissues and their dysfunction can cause various diseases.

Compounds from certain trees used by First Nations people show potential for treating skin conditions and promoting hair growth, but more research is needed to confirm their safety and effectiveness.

Curcumin supplements increase adiponectin and decrease leptin in adults.

MED1 is essential for normal hair growth and maintaining hair follicle stem cells.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

The document concludes that primary scarring alopecias cause permanent hair loss, have unpredictable outcomes, and lack definitive treatments, requiring personalized care.

Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.

Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.

Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.