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Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Cannabinoids may help treat various skin conditions.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.

Human hair follicles contain a complex network of prostanoid receptors that may influence hair growth.

The document concluded that more research is needed to find the best treatment for Frontal fibrosing alopecia.

A man with complete hair loss and ulcerative colitis regrew hair after treatment with azathioprine.

Cabergoline helped a boy with Cushing disease get better after surgery and radiotherapy didn't work.

New understanding and treatments for hair loss are improving, but more research is needed.

Dermal adipose tissue in mice can change and revert to help with skin health.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.

DHEA affects various tissues by interacting with multiple receptors and can be converted into sex hormones.

Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.

Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.

Finasteride harms Daphnia magna's reproduction, growth, and metabolism.

YH0618 helps reduce chemotherapy-induced hair loss by targeting specific proteins and pathways.

People with Primary Cicatricial Alopecia have a higher risk of heart disease.

New treatments for hair loss should target eight main causes and use specific plant compounds and peptides for better results.

Insulin resistance increases the risk of developing type 2 diabetes and other health issues.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

Vitamin D might help regulate insulin in the body, but taking Vitamin D supplements doesn't clearly prevent or improve type 2 diabetes. More research is needed.

Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.

Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.

Alopecia areata is an incurable autoimmune condition causing hair loss, with research aiming for better treatments.

Five preservatives may disrupt hormone function and need more health and environmental risk assessment.

Thyroid hormone receptors are essential for hair growth and wound healing.

Topical immunotherapy can treat alopecia areata, but its effectiveness varies and the exact mechanism is unclear.

Activating Nrf2 can help protect against hearing loss.

New treatments like nanotechnology show promise in improving skin cancer therapy.