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Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

PGD2 stops hair growth and is higher in bald men with AGA.

Some medicinal plants can help heal wounds and may lead to new treatments.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Minoxidil effectively treats hair loss, but use cautiously and monitor side effects.

No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Scientists created stem cells that can grow hair and skin.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.

Fatty acid transport protein 4 is essential for skin and hair development.

Researchers identified genes linked to coat color, body size, cashmere production, and high altitude adaptation in goats.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

Type 2 diabetes, bacterial scalp infections, and tight hairstyles like braids and weaves are linked to a higher risk of a scarring hair loss condition in African American women.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

The circadian clock influences the behavior and regeneration of stem cells in the body.

The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.

Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.