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This review highlights that while dexamethasone may reduce mortality in severe COVID-19, no other drugs have proven effectiveness for treatment, emphasizing the need for clinical trials of existing medications.

This study found that cepharanthine can inhibit gastric cancer cell activity by inducing oxidative stress and altering energy metabolism, suggesting its potential for gastric cancer treatment.

This review discusses the roles of tissue-specific and mesenchymal stromal cells in tissue repair and reparative disorders, highlighting potential therapeutic targets for muscle, heart, and lung tissues.

This review discusses the role of sex hormones in cardiac hypertrophy and notes that estrogen provides protection against hypertrophy in pre-menopausal women, which is reduced after menopause but partially restored with estrogen therapy.

This study found that extracellular ATP released from UVB-irradiated keratinocytes promotes melanin production through the P2X7 receptor, indicating a role for ATP-P2X7 signaling in UV-induced melanogenesis.

This study examined the structural and biochemical mechanisms of human lipocalin prostaglandin D synthase, detailing substrate and product binding processes at the catalytic site and suggesting potential for drug delivery targeting hydrophobic molecules.

This review discusses how neurosteroids acting on GABAA receptors may influence behavior and explores the potential for developing selective modulators for treating psychiatric disorders, but reports no new clinical results.

This review discusses hair follicle stem cells for wound healing and reports no new clinical results, noting their potential but emphasizing the need for further understanding and safety in clinical applications.

This review discusses the role of acyl-CoA binding protein (ACBP) in the epidermal barrier, noting that its disruption in mice is linked to skin and fur abnormalities; it reports no new clinical results.

This study found that PBX1 overexpression reduces hair follicle-derived mesenchymal stem cell senescence and apoptosis by interacting with SIRT1 and PARP1, highlighting a potential mechanism for addressing aging-related diseases.

This review discusses the role of hair follicle bacterial colonization in immune responses and the pathogenesis of alopecia but reports no new clinical results.

This review discusses various theories of skin aging and the importance of using professional and at-home skincare solutions, but offers no new empirical findings.

This study found that topical application of TSG from Polygonum multiflorum promoted hair regrowth in depilated mice, potentially through the inhibition of apoptosis-related proteins.

This study found that integrin-linked kinase is crucial for various epidermal functions, including differentiation and barrier formation, and also plays a previously unreported role in melanocyte development and function.

This review examines the pharmacological potential of quinoline alkaloids from Cinchona bark for developing new drugs and cosmetics but reports no new findings.

This study found that Rumex japonicus Houtt. root extract promoted hair growth by enhancing cell proliferation and preventing apoptosis in human dermal papilla cells and HaCaT cells, as well as in a mouse model.

This study suggests that finasteride treatment in male rats can lead to changes in liver carbohydrate metabolism and may result in metabolic disruptions and liver steatosis in their offspring.

This study reports that mesenchymal stem cell-conditioned medium promoted dermal cell migration and proliferation, enhancing wound healing but not direct hair growth, in vitro and in adult mouse models.

In this study, saw palmetto supplements showed varied effects on cell growth in vitro and did not significantly inhibit growth in the hamster flank organ model despite a notable trend.

This study identified key genes and pathways involved in the seasonal hair cycle regulation of yak, uncovering molecular mechanisms that may aid in understanding their adaptation to alpine environments.

This study found that cephalanthine inhibited the growth of gastric cancer cells in vitro and in vivo by inducing oxidative stress and altering energy metabolism, suggesting its potential as a treatment for gastric cancer.

This chapter reviews existing knowledge about melatonin's MT₁ and MT₂ receptors in human tissues, discussing their established and potential functions, but reports no new clinical findings.

In this study, the researchers identified a PBX1-SIRT1-PARP1 axis that plays a crucial role in reducing senescence and apoptosis in hair follicle-derived mesenchymal stem cells.

Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.

This review examines the relationship between glycation, insulin resistance, and PCOS, discussing various treatments and highlighting M. oleifera and S. platensis as potential therapeutic agents, but reports no new clinical results.

In this review, the authors discuss various skin conditions linked to hyperandrogenism, such as acne and alopecia, with a focus on androgen-targeted therapies, suggesting these are generally more effective than non-androgen-targeted options.

This review discusses the potential impact of lifestyle factors on the progression of androgenetic alopecia and reports no new clinical findings; the authors emphasize the need for more comprehensive studies.

This study investigated the molecular mechanisms behind cashmere goat coat types by analyzing gene expression during hair follicle development stages, identifying regulatory pathways involved in metabolism, immune response, and the quiescent state of follicles, potentially aiding in genetic selection for improved cashmere production.

This review reports that hair follicles are dynamic neuro-immuno-endocrine organs with intrinsic signaling pathways, which play a crucial role in hair disorders like alopecia. It highlights emerging regenerative approaches targeting these pathways for hair restoration.

This review discusses the heterogeneity of Tregs in normal and tumor environments, emphasizing the complexity of targeting tumor-resident Tregs while maintaining systemic immune tolerance, but reports no new findings.