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Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Skin fat plays a key role in immune defense and healing beyond just storing energy.

Researchers created rat liver stem cells that could help repair liver failure in rats and may be useful for studying human liver diseases.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Asian hair is generally straight and thick, with unique disorders and properties, and more research is needed to understand it fully.

Insulin-lowering medications show promise for PCOS symptoms but can't be the main treatment yet due to limited long-term research.

Some treatments like intralesional steroids and 5α-reductase inhibitors are effective for frontal fibrosing alopecia, but more research is needed.

The document concludes that treating PCOS requires a combination of drugs to manage reproductive and metabolic symptoms, with more research needed on combination therapies.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Some Middle Eastern plants may help treat diabetes and could be alternatives to current drugs, but more research is needed.

Caffeine applied to the scalp can protect hair follicles from UV damage.

The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.

Continuous light exposure in rats leads to PCOS-like symptoms and suggests sleep habits might affect the disorder's development.

A team approach is crucial for managing PCOS, with dermatologists playing a key role.

Longer hair loss leads to more severe CCCA; early treatment and avoiding damaging hairstyles help regrowth.

Girls with PCOS during adolescence have a higher risk of developing type 2 diabetes, and early treatment can help manage this risk.

The document concludes that there is a significant lack of reporting on the sex and age of cells in skin research, which could affect clinical trials and treatments.

The document concludes that primary scarring alopecias cause permanent hair loss, have unpredictable outcomes, and lack definitive treatments, requiring personalized care.

lncRNA XLOC_008679 and gene KRT35 affect cashmere fineness in goats.

Hair loss in cancer patients can be related to the cancer itself, treatment, or other conditions, and understanding it is important for diagnosis and patient care.

Mutations in certain receptors can cause diseases and offer new treatment options.

Indigenous herbal medicines in the Indian subcontinent have potential for drug development but need more research and standardization.

The document concludes that understanding hair follicles requires more research using computational methods and an integrative approach, considering the current limitations in hair treatment products.

DNA methylation and long non-coding RNAs are key in controlling hair growth in Cashmere goats.

Some plants with flavonoids may help treat hair loss and promote hair growth.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.