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    Glossary POU domain

    specific protein region that binds DNA to regulate genes

    The POU domain is a specific region found in certain proteins that bind to DNA and regulate gene expression. Named after three transcription factors (Pit-1, Oct-1/2, and Unc-86), this domain is crucial for the development and function of various tissues, including the nervous system and the immune system.

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    1. Characterization of Mouse Profilaggrin: Evidence for Nuclear Engulfment and Translocation of the Profilaggrin B-Domain during Epidermal Differentiation 2002 · 25 citations
    2. The History of Hair Transplantation Dermatologic Surgery · 2000 · 15 citations
    3. The epidermis: rising to the surface Current opinion in genetics & development · 1994 · 238 citations
    4. Hox genes in development and beyond Development · 2023 · 83 citations
    5. Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth-Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development Cells · 2019 · 136 citations
    6. A role for p75 neurotrophin receptor in the control of apoptosis‐driven hair follicle regression The FASEB Journal · 2000 · 96 citations
    7. Stem cells from human hair follicles: first mechanical isolation for immediate autologous clinical use in androgenetic alopecia and hair loss Stem cell investigation · 2017 · 86 citations
    8. Systematic Review of Platelet-Rich Plasma Use in Androgenetic Alopecia Compared with Minoxidil®, Finasteride®, and Adult Stem Cell-Based Therapy International Journal of Molecular Sciences · 2020 · 65 citations
    9. Autologous Micrografts from Scalp Tissue: Trichoscopic and Long-Term Clinical Evaluation in Male and Female Androgenetic Alopecia BioMed Research International · 2020 · 41 citations
    10. Stem Cell-Based Hair Cell Regeneration and Therapy in the Inner Ear Neuroscience Bulletin · 2023 · 26 citations
    11. Proteomic analysis of balding and non-balding mesenchyme-derived dermal papilla cells from androgenetic alopecia patients using on-line two-dimensional reversed phase-reversed phase LC–MS/MS Journal of Proteomics · 2013 · 11 citations
    12. Hétérogénéité tumorale du cancer de la prostate et infection par le SARS-CoV2 : une relation complexe impliquant les vésicules extracellulaires et le récepteur des androgènes SPIRE - Sciences Po Institutional REpository · 2023
    13. Microarray analysis of androgenetic and senescent alopecia: Comparison of gene expression shows two distinct profiles Journal of Dermatological Science · 2013 · 27 citations
    14. Candidate SNP markers of reproductive potential are predicted by a significant change in the affinity of TATA-binding protein for human gene promoters BMC Genomics · 2018 · 16 citations
    15. The pioneer factor SOX9 competes for epigenetic factors to switch stem cell fates Nature cell biology · 2023 · 6 citations
    16. Organogenesis From Dissociated Cells: Generation of Mature Cycling Hair Follicles From Skin-Derived Cells Journal of Investigative Dermatology · 2005 · 205 citations
    17. Construction strategies of skin organoids: A review Organoid Research · 2026
    18. Physiopathological role of the enzymatic complex 5α-reductase and 3α/β-hydroxysteroid oxidoreductase in the generation of progesterone and testosterone neuroactive metabolites Frontiers in Neuroendocrinology · 2020 · 18 citations
    19. Role of OCT4 in the Regulation of FSH-Induced Granulosa Cells Growth in Female Mice Frontiers in Endocrinology · 2020 · 14 citations
    20. Tanshinone IIA pretreatment protects free flaps against hypoxic injury by upregulating stem cell-related biomarkers in epithelial skin cells BMC Complementary and Alternative Medicine · 2014 · 13 citations
    21. Identification and dissection of an enhancer controlling epithelial gene expression in skin Proceedings of the National Academy of Sciences · 2001 · 29 citations
    22. OCT4 maintains self-renewal and reverses senescence in human hair follicle mesenchymal stem cells through the downregulation of p21 by DNA methyltransferases Stem Cell Research & Therapy · 2019 · 57 citations
    23. Transcriptional regulation analysis and the potential transcription regulator site in the extended KAP6.1 promoter in sheep Molecular Biology Reports · 2014 · 5 citations
    24. H3K9me3 controls epidermis morphogenesis by regulating RNA Pol II dynamics at developmental promoters and enhancers Nature Communications · 2026
    25. Calcium regulation of stem cells EMBO reports · 2020 · 25 citations
    26. Proof-of-Principle Study of Inflammasome Signaling Proteins as Diagnostic Biomarkers of the Inflammatory Response in Parkinson’s Disease Pharmaceuticals · 2023 · 17 citations
    27. Inflammasome Proteins Are Reliable Biomarkers of the Inflammatory Response in Aneurysmal Subarachnoid Hemorrhage Cells · 2024 · 4 citations
    28. Human Induced Pluripotent Stem Cell–Derived Ectodermal Precursor Cells Contribute to Hair Follicle Morphogenesis In Vivo 2013 · 64 citations
    29. Isolation of a Novel Population of Multipotent Adult Stem Cells from Human Hair Follicles American Journal Of Pathology · 2006 · 344 citations
    30. Regulation of Involucrin Gene Expression Journal of Investigative Dermatology · 2004 · 138 citations