January 2018 in “日本薬理学会年会要旨集 =” Minoxidil may protect the brain from damage by preventing cell death and energy loss.
22 citations,
February 2007 in “Developmental neurobiology” Hormones and sex affect potassium channel gene expression in electric fish, influencing their communication signals.
102 citations,
June 2008 in “The FASEB Journal” One minoxidil-sensitive potassium channel exists in human hair follicles.
22 citations,
February 2008 in “Journal of Neurochemistry” Minoxidil prevents serotonin loss from MDMA by affecting potassium channels and increasing Akt phosphorylation.
9 citations,
December 2017 in “Pharmacological Reports” ATP-sensitive potassium channels play a role in chloroquine-induced itch in mice.
5 citations,
September 2022 in “Molecular pharmacology” KATP channels are important for energy balance and are targeted by drugs for diabetes, hypoglycemia, hypertension, and hair loss.
Activating certain potassium channels in honey bees can lower antioxidant levels and reduce death rates during heavy mite infestations, potentially aiding their immune response.
4 citations,
January 1994 in “Yakugaku zasshi” EPC-K is stable except at very acidic pH or when exposed to sunlight, and it can decompose in low ethanol concentrations.
397 citations,
February 2004 in “British Journal of Dermatology” Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.
119 citations,
July 2005 in “Journal of Molecular and Cellular Cardiology” Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.
48 citations,
June 1988 in “PubMed” Minoxidil sulfate relaxes muscle by increasing potassium flow, making it a unique muscle relaxer.
33 citations,
May 1991 in “British Journal of Pharmacology” Cromakalim relaxes various blood vessels, while minoxidil sulphate is more selective; they likely act on different potassium channels.
4 citations,
December 2013 in “International Journal of Dermatology” Three children with nasal fungal infections were successfully treated with potassium iodide and sometimes itraconazole.
1 citations,
July 2019 in “Farmatsevtychnyĭ zhurnal” The optimal gel-mask for hair loss contains 15% nettle juice, 0.5% carbopol ultrez 10 and sodium alginate, 0.1% potassium sorbate, and 0.4% PEG-40 hydrogenated castor oil.
1 citations,
December 2016 in “Vìsnik farmacìï” The best gel to treat a type of hair loss has 1% sodium alginate, 1% carbopol, 5% glycerin, 0.2% potassium sorbate, and water.
Depressed individuals have higher hair sodium and potassium levels, similar to changes seen in astronauts.
July 2023 in “JCEM Case Reports” A 36-year-old woman with low potassium levels was found to have Cushing disease, and after treatment, her potassium levels normalized.
47 citations,
October 1989 in “Circulation Research” The study explains how minoxidil sulfate causes vasodilation in rabbits by opening potassium channels and inhibiting calcium channels.
3 citations,
March 2023 in “American journal of physiology. Cell physiology” Inward rectifier potassium channels are important in many body functions and diseases, and could be potential drug targets.
1 citations,
January 2023 in “General physiology and biophysics” Minoxidil relaxes rat blood vessels mainly through nitric oxide and potassium channels.
152 citations,
May 2012 in “Recent Patents on Inflammation & Allergy Drug Discovery” Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.
82 citations,
July 2016 in “Autoimmunity reviews” Animal models have helped understand hair loss from alopecia areata and find new treatments.
42 citations,
March 2006 in “Drug Discovery Today: Therapeutic Strategies” The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
35 citations,
February 2012 in “The New England Journal of Medicine” Early diagnosis and treatment of TPP can prevent complications.
33 citations,
April 1990 in “Dermatologic Clinics” Minoxidil effectively treats hair loss, with better results in women.
26 citations,
January 1990 in “Mycoses” Most tinea capitis cases in Rotterdam were caused by Trichophyton violaceum, mainly affecting Moroccan immigrant children.
24 citations,
January 2012 in “Journal of natural science, biology and medicine” Tinea capitis is common among Kolkata school children, especially boys, and hygiene doesn't greatly impact infection rates.
16 citations,
May 2020 in “Frontiers in pharmacology” Minoxidil can stop the growth of ovarian cancer cells without harming the heart.
13 citations,
January 2012 in “International journal of trichology” The study found that hair fragility in Pili annulati may be caused by cavities and damage within the hair shafts.
13 citations,
March 2002 in “Pediatric Dermatology” A child was initially wrongly diagnosed with a fungal scalp infection but actually had a non-scarring hair loss condition called Temporal Triangular Alopecia.