11 citations,
October 2019 in “Cancers” Spironolactone may make some cancer treatments more effective by blocking a protein that helps cancer cells survive.
5 citations,
January 2016 in “Asian pacific Journal of Tropical Biomedicine” Phthirusa pyrifolia extract may lower testosterone and harm male rat reproduction without damaging the liver or kidneys.
119 citations,
June 2005 in “Journal of Molecular and Cellular Cardiology” Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.
28 citations,
August 2013 in “Hypertension” Potassium channel openers help form elastic fibers in arteries and can treat elastin deficiency and hypertension.
397 citations,
February 2004 in “British Journal of Dermatology” Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.
33 citations,
May 1991 in “British Journal of Pharmacology” Cromakalim relaxes various blood vessels, while minoxidil sulphate is more selective; they likely act on different potassium channels.
19 citations,
February 2016 in “Journal of Biological Chemistry” KCNQ potassium channels help control the sensitivity of touch receptors in the skin.
17 citations,
January 2013 in “Indian Journal of Pharmacology” High levels of the seizure medication sodium valproate can cause hair loss.
13 citations,
September 2019 in “Scientific Reports” High levels of the protein Flightless I worsen ulcerative colitis symptoms in mice.
4 citations,
February 2021 in “Plant journal” OsUEV1B protein is essential for controlling phosphate levels in rice.
1 citations,
October 2023 in “The Journal of nutrition, health & aging” Higher hair levels of zinc and chromium were linked to less cognitive decline in very old people.
July 1999 in “Liver transplantation and surgery” Oxygen levels can drop during liver transplant if bypass pressures are too high, but other reasons should be checked first.
50 citations,
March 2011 in “European Journal of Endocrinology” Spironolactone improved blood vessel function and cholesterol levels in non-obese women with PCOS.
4 citations,
January 2010 in “Acta dermato-venereologica” Low androgen levels can still cause female pattern hair loss.
2 citations,
September 2004 in “Fertility and sterility” High androgen levels can cause excessive hair growth and may indicate serious health issues, including heart disease and fertility problems.
May 2002 in “British Journal of Dermatology” A pregnant woman's skin condition improved after giving birth, possibly due to high estrogen levels during pregnancy.
59 citations,
September 1994 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.
47 citations,
October 1989 in “Circulation Research” The study explains how minoxidil sulfate causes vasodilation in rabbits by opening potassium channels and inhibiting calcium channels.
19 citations,
December 2016 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics” Certain drugs increase calcium levels in cancer cells by triggering internal calcium release.
19 citations,
July 1993 in “Journal of Applied Toxicology” Different oil products cause varying levels of skin irritation in mice, which could potentially lead to tumors.
18 citations,
July 2014 in “Molecular Medicine Reports” UVB radiation changes the levels of certain microRNAs in skin cells, which may affect cell survival and hair growth.
17 citations,
February 2019 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.
8 citations,
October 2014 in “Journal of analytical toxicology.” Chemical hair straightening significantly reduces detectable drug levels in hair.
August 1994 in “Molecular Endocrinology” Changing protein kinase levels in pituitary cells affects calcium flow and beta-endorphin release.
Jockeys using diuretics without potassium supplements can face health problems.
10 citations,
July 2019 in “Journal of Asia-Pacific Entomology” Different silkworm varieties have varying nutrient levels in their powders, which may promote hair growth.
6 citations,
June 2011 in “British Journal of Dermatology” People with alopecia areata have higher levels of RBP4 protein and antibodies against it.
6 citations,
August 2009 in “Mini-reviews in Medicinal Chemistry” Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.
5 citations,
May 2023 in “Frontiers in immunology” Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.
1 citations,
July 2017 in “The Journal of Urology” Low-dose finasteride and dutasteride reduce PSA levels by 27.8% in men with male androgenetic alopecia.