January 2024 in “Journal of Natural Remedies” This study found that the petroleum ether extract of Solanum nigrum may promote hair regrowth in testosterone-induced hair loss in rats, as indicated by increased follicle density and anagen/telogen ratio.
November 2023 in “Materials Today Bio” This article discusses photobiomodulation as a potential adjunct to hair follicle organoid culture for androgenic alopecia, reporting no new results and suggesting further study is needed.
This review highlights the therapeutic potential of hair follicle stem cells in tissue repair and hair regeneration, discussing the molecular mechanisms and the impact of natural compounds on stem cell properties, which may support the development of novel hair loss treatments.
June 2023 in “Journal of Ayurvedic and herbal medicine” This review article highlights the potential health benefits and pharmaceutical components of pumpkin seeds, which contain proteins, antioxidants, and essential nutrients, and discusses their traditional medicinal uses and emerging applications in the food industry.
October 2022 in “Amplla Editora eBooks” August 2022 in “Ad-Dawaa' Journal of Pharmaceutical Sciences” This study found that a combination of H. rosa-sinensis L. and B. racemosa extracts produced the most hair follicles in stress-induced alopecia in male Wistar albino rats.
January 2022 in “Springer eBooks” This chapter reviews the clinical evidence of adding platelet-rich plasma to lipofilling for tissue regeneration, with suggestions of benefits in skin rejuvenation and wound healing, but lacks well-designed trials.
January 2022 in “Przegla̧d dermatologiczny” This article reviews potential causes of frontal fibrosing alopecia but does not provide new clinical findings.
January 2022 in “Social Science Research Network” This study found that most potassium channel blockers increased the activity of slowly adapting mechanoreceptors in rat whisker pads, while the opener NS1619 decreased their evoked activity.
January 2022 in “International Journal of Pharmacognosy and Pharmaceutical Sciences” This review examines the ethanomedicinal uses and pharmacological properties of Semecarpus anacardium, commonly used in traditional medicine, and does not provide new clinical results; it highlights a range of potential benefits including anti-inflammatory and antioxidant activities.
This narrative review examined the potential of hibiscus leaves and apple skin as natural ingredients for hair tonics and reported their effectiveness in addressing hair loss, highlighting properties like strong antioxidant content and ability to strengthen hair roots.
August 2020 in “Prosiding Farmasi” This review explores the potential of Arabian Bidara leaves as a hair growth enhancer based on its shared chemical compounds with other known hair-fertility-promoting plants, but it reports no new experimental results.
May 2020 in “Jurnal Penelitian Perawat Profesional” This literature review identified that katuk leaves, rich in vitamins and phenolic compounds, show potential in preventing hair loss by promoting hair growth, enhancing vascularity, and nourishing hair.
January 2020 in “Archives of Pharmacy Practice” This study found that Hibiscus rosa-sinensis leaf extract promoted hair growth in rats more effectively than its flower extract, suggesting its potential as a natural alternative for hair growth treatments.
June 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that atopic dermatitis patients had a 30% lower prevalence of benign paroxysmal positional vertigo, with socioeconomic factors influencing these patterns.
In this study, researchers developed isotretinoin-loaded Delonix polymeric nanoparticles that target hair follicles and found they effectively sustained drug release, reduced IL-6 production in vitro without inhibiting P. acnes, and may prevent isotretinoin-related skin irritation in vivo in Wistar rats.
In this animal study, leaf extracts of Kalanchoe pinnata increased hair length in rabbits in a concentration-related manner, surpassing minoxidil at the highest concentration, though hair mass was unaffected.
January 2018 in “日本薬理学会年会要旨集 =” This study found that high-dose minoxidil, a potassium channel opener, may protect neuronal tissue from damage following transient focal cerebral ischemia in mice.
PRP hair treatment is generally safe but may cause minor pain, bleeding, redness, and scalp tightness, and isn't suitable for everyone.
January 2012 in “Journal of Natural Remedies” This study found that the aqueous extract of Abrus precatorius leaf promoted hair growth in experimental settings, with effects comparable to 2% minoxidil.
November 2009 in “Eclética Química” In this study, a potentiometric titration method was developed for determining minoxidil, achieving recoveries of 97.4% to 98.7%, and it showed agreement with a chromatographic procedure at a 90% confidence level.
January 2008 in “Springer eBooks” Thyroid hormone may be useful for treating various skin conditions and needs more research.
January 2006 in “Chinese Journal of Medical Aesthetics and Cosmetology” This study found that microencapsulated human hair dermal papilla cells successfully induced hair follicle regeneration on the dorsal skin of nude mice, unlike control groups with free cells or empty microcapsules.
December 2022 in “International journal of research publications” This review explores the potential of herbal medicine as an alternative treatment for alopecia areata, suggesting it could improve patient recovery, but reports no new clinical results.
April 2019 in “Advances in integrative medicine” This study found that the highest rebound value in concrete with high volume slag occurs with 40% slag content, 10–20 mm basalt aggregates, and greater carbonation depth.
216 citations
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September 2020 in “Scientific African” This review discusses the potential of pumpkin seeds as a functional food ingredient, highlighting their promising bioactive compounds and health benefits, but reports no new clinical results.
165 citations
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January 2006 in “Molecular Medicine” This review highlights the role of matriptase in epithelial differentiation and cancer, noting that unregulated matriptase expression can enhance cancer progression in animal models, but reports no new experimental data.
111 citations
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August 2002 in “Journal of Medicinal Chemistry” This study reports that 2-(1-Adamantyl)-4H-thiochromen-4-on-6-O-sulfamate is the most potent steroid sulfatase inhibitor identified so far, exhibiting 170-fold higher activity than the lead compound estrone sulfamate.
80 citations
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September 2007 in “Cell Cycle” This study found that nestin-expressing cells in the hair follicle bulge exhibit multipotent stem cell-like properties and can generate neural cells both in vitro and in vivo.
73 citations
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August 2008 in “Chinese Journal of Traumatology” This review outlines recent advances in using stem cells for skin repair and regeneration, suggesting potential for complete skin and appendage regeneration after severe burns, but presents no new clinical findings.