131 citations
,
January 2018 in “Scientific Reports” In this study, mycorrhizal fungal inoculation was associated with increased root-hair growth and enhanced drought tolerance in trifoliate orange by modulating auxin synthesis and transport under water stress conditions.
125 citations
,
September 2019 in “Journal of Clinical Immunology” This review summarizes recent advances in Treg cell biology, focusing on Foxp3's role in immune regulation and therapeutic reprogramming for immune dysregulatory disorders, but reports no new clinical results.
112 citations
,
November 2023 in “Nano-Micro Letters” This review discusses the developments over the past five years in nanozyme-based theranostics for tumor therapy, including their classification, design, and synergistic strategies. It also outlines the challenges and prospects of using nanozymes to enhance selectivity, biosafety, repeatability, and stability in therapeutic applications.
111 citations
,
August 2002 in “Journal of Medicinal Chemistry” This study reports that 2-(1-Adamantyl)-4H-thiochromen-4-on-6-O-sulfamate is the most potent steroid sulfatase inhibitor identified so far, exhibiting 170-fold higher activity than the lead compound estrone sulfamate.
58 citations
,
April 1998 in “Journal of biological chemistry/The Journal of biological chemistry” This study identified that the enzyme CYP2B12 is skin-specific and likely plays a role in the metabolism of arachidonic acid, a key component in lipid signaling within sebaceous glands.
40 citations
,
October 2009 in “Journal of Biomedical Nanotechnology” This review discusses pyrene excimer nucleic acid probes for detecting biomolecules and protein-DNA interactions and reports no new experimental findings.
38 citations
,
June 2018 in “Plant & cell physiology/Plant and cell physiology” This study found that overexpressing PLC5 in Arabidopsis thaliana reduced root growth but improved drought tolerance, and suggests PIP2 is crucial for root hair growth.
30 citations
,
March 2019 in “Archives animal breeding/Archiv für Tierzucht” In this study, variation in the KRTAP15-1 gene in goats was linked to changes in cashmere fibre diameter, with specific variants showing dominant or recessive effects.
22 citations
,
February 2010 in “The Veterinary clinics of North America. Small animal practice/Veterinary clinics of North America. Small animal practice” This article reviews the evidence regarding the role of sex hormones in occult hyperadrenocorticism and reports no new findings, highlighting the unproven nature of their involvement.
22 citations
,
August 2009 in “Evidence-based Complementary and Alternative Medicine” This study found that a composition including Serenoa repens extract and anti-inflammatory agents effectively suppressed inflammation-related gene expression in a keratinocyte model, suggesting a potential dual strategy for treating androgenetic alopecia.
21 citations
,
October 2014 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” This review discusses the role of hair dyes in cosmetic dermatology, their effects on hair and scalp health, and the importance of dermatologists understanding potential side effects; it reports no new findings.
20 citations
,
September 2015 in “Protein expression and purification” This study demonstrated that safflower seeds can be engineered to express oleosin-FGF10, which showed a dose-dependent effect on cellular proliferation, potentially facilitating scalable protein production.
18 citations
,
December 2006 in “Clinical dysmorphology” This article reviews the case of a 2-year-old boy with rhombencephalosynapsis and considers its potential links to Gomez–López-Hernández syndrome, suggesting further research into its genetic causes; no new clinical results are reported.
17 citations
,
March 2020 in “Frontiers in Chemistry” This study isolated new geranylated coumarins from Mammea siamensis flowers and found that several of these compounds inhibit testosterone 5α-reductase.
17 citations
,
January 2019 in “Journal of cancer” This study found that the medicinal formula YH0618 may reduce toxicity from the chemotherapy drug doxorubicin, improving side effects like hair loss and organ damage, while maintaining its anti-cancer effects.
16 citations
,
September 2020 in “British journal of dermatology/British journal of dermatology, Supplement” This review explores the role of neutrophil recruitment in the inflammation seen in hidradenitis suppurativa and emphasizes potential therapeutic targets within these pathways, but it reports no new clinical results.
16 citations
,
December 2018 in “Plant Science” This study found that elevated carbon dioxide levels may help mitigate water deficit stress in soybean roots by altering gene expression related to stress and nutrient transport.
15 citations
,
July 2004 in “Journal of morphology” This study analyzes the fine structure and protein distribution in monotreme hairs, finding similarities with other mammals and detailing unique immunocytochemical features in their inner root sheaths.
14 citations
,
July 2017 in “Monatshefte für Chemie - Chemical Monthly” This review discusses the analysis of pharmaceutical relics from prehistoric times to the twentieth century and emphasizes the need for a multifaceted approach, but it presents no new experimental results.
12 citations
,
April 2023 in “Nano Biomedicine and Engineering” This study synthesized silver nanoparticles using an Artocarpus heterophyllus leaf extract and found that these nanoparticles, with a size of 100–110 nm, displayed effective antioxidant, antibacterial, and antifungal activities in vitro.
12 citations
,
January 1978 in “The Laryngoscope” This article describes the successful use of parieto‐occipital flap operations for hereditary or traumatic baldness but reports no new clinical results.
8 citations
,
December 2020 in “Scientific reports” This study examined the genetic basis for the curly hair trait in Mangalitza pigs, finding two specific genetic variants that contribute to this distinctive phenotype through autosomal dominant inheritance.
7 citations
,
January 1995 in “Journal American Society of Mining and Reclamation” This review discusses the forms of selenium and sulfur in soil, their plant absorption, and risks of toxicity to livestock, emphasizing selenium's role in selenosis and sulfur's link to polioencephalomalacia in ruminants; it reports no new experimental results.
6 citations
,
February 2023 in “Plant and Soil” This study found that volatile organic compounds from Bacillus subtilis strain WM13-24 enhanced root development in Arabidopsis and its host plant through auxin signaling.
4 citations
,
October 2016 This source describes the potential of various herbal treatments, such as aloe vera and amla, as natural alternatives for managing hair loss and enhancing hair health, noting their benefits include fewer side effects, affordability, and multiple application methods.
4 citations
,
December 2009 in “Elsevier eBooks” This review discusses the nutritional and medicinal benefits of breadfruit and highlights challenges in promoting its consumption, but reports no new empirical findings.
3 citations
,
August 2015 in “Diabetes and Metabolic Syndrome: Clinical Research and Reviews” This study suggests that type 2 diabetes mellitus and polycystic ovary syndrome are separate medical entities despite both being linked to insulin resistance.
2 citations
,
September 2023 in “Frontiers in sustainable food systems” This study found that Sinja Valley residents possess traditional knowledge of 13 edible oil-producing plant species, yet this knowledge is at risk due to sociocultural changes. Despite its benefits, including treating disorders like gastritis, use of indigenous oils is declining as commercial products become prevalent.
2 citations
,
March 2023 in “Frontiers in medicine” This case report presents the first successful treatment of perifolliculitis capitis abscedens et suffodiens using a regimen of adalimumab and baricitinib, resulting in almost complete healing after nine months.
2 citations
,
March 2019 in “European Journal of Dermatology” This study concluded that shampoos sold in pharmacies generally contain fewer regulated allergens under EU law compared to those sold in mass-market stores or by mail order, and pharmacy-sold baby shampoos were allergen-free.