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Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

EGFR inhibitors often cause skin problems and other side effects, but these are usually reversible and can be managed to keep patients comfortable.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

PLD is an effective and safer alternative for treating breast cancer.

Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.

Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.

Memantine may slightly improve memory in people with Down syndrome, but more research is needed.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Prostate cancer prevention includes diet changes, supplements, and medications, with more answers expected soon.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Certain proteins, caspases-1 and -11, are important in the early development of skin inflammation in mice.

Edible seeds from the Cucurbitaceae family like pumpkin and watermelon seeds are nutritious and may have health benefits, but eating too much can cause side effects.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.

The document concludes that more research is needed to understand how to treat muscle pain with drugs.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.

α3β1-integrin is crucial for maintaining normal hair follicle shape and function but not needed for the development of the surrounding skin.

Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.

Stress from being transgender is linked to higher blood pressure at night and more inflammation, which may affect heart health.

Plant-based ingredients are effective and safe for modern skincare products.

Using steroids can increase the risk of heart problems.