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Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

The document explains the causes, types, diagnosis, and treatments of hair loss, and its psychological impact, especially on women.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Finasteride improves immune response and reduces organ damage after trauma hemorrhage in mice.

Older adults use lifestyle drugs to improve life quality and appearance, but caution is needed due to side effects and potential abuse.

Certain cultural hair practices might cause baldness by affecting natural hair oils and stem cell delivery to hair follicles.

Continuous research and innovative strategies are essential for sustainable development.

New medications are improving depression treatment, emphasizing accurate diagnosis and chronic care.

Hair cortisol may be a good indicator of recent mood in people with bipolar disorder.

Higher dihydrotestosterone may be linked to more inflammation in COVID-19 patients with low testosterone.

Sodium valproate caused vomiting, hair loss, loss of appetite, abdominal pain, weight gain, and anemia in young children with epilepsy.

The review suggests doctors should carefully weigh risks and benefits of off-label drug use, involve patients in decisions, and calls for better regulations and monitoring.

A man developed a rare late-onset hair-pulling disorder, usually seen in younger people.

Computational methods can speed up and improve the development and safety of herbal drugs.

Off-label drug use can be risky but sometimes beneficial when standard treatments fail.

The conclusion is that using the 5W1H method can improve diagnosis and management of childhood hair-pulling disorder.

Impulsiveness is common across various psychiatric disorders and linked to many psychological symptoms.

The document's conclusion cannot be provided because the document is not readable or understandable.

Long COVID is a serious, long-lasting illness that needs more recognition and support.

Chronic arsenic exposure can cause liver damage and other health issues.

COVID-19 can cause over 50 long-term symptoms, with fatigue and headache being the most common.

A protein called HMGB1 helps hair grow by affecting prostaglandin metabolism.

Female guinea pigs exposed to less allopregnanolone before birth showed more anxiety-like behavior.

Recognizing and managing central sensitization and stress is crucial for treating chronic pain.

COVID-19 diagnosis is linked to new or worsening hair diseases, with stress from the pandemic likely contributing.

The document's conclusion cannot be provided because the content is not accessible or understandable.

Platelet-rich plasma therapy helps increase hair thickness and slow hair loss.

Hair transplantation is effective for treating scar-related hair loss on the head and neck.

COVID-19 may worsen hair loss, and Nourkrin® could be a safe treatment option, but more research is needed.

Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.