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The document concludes that computational methods using networks and various data can improve the process of finding new uses for existing drugs.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.

Serenoa repens (saw palmetto) may cause side effects like hot flashes in children and needs more research for safety in pediatric use.

Rapamycin may help treat Leigh syndrome by targeting protein kinase C.

Minoxidil may help reduce aging effects in brain cells.

Older adults use lifestyle drugs to improve life quality and appearance, but caution is needed due to side effects and potential abuse.

Modified HDL can better deliver drugs and genes, potentially improving treatments and reducing side effects.

Hydroxyl radicals cause hair follicle cell death during chemotherapy by reducing Bcl-2 protein levels.

Taking 1 mg of finasteride daily can increase hair count and improve hair appearance, but it may have side effects on sexual function and a potential risk of prostate cancer. It may not be effective for postmenopausal women unless taken in higher doses.

Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.

The document concludes that managing skin conditions during pregnancy is important and requires specialized care.

Survivors of Stevens-Johnson syndrome/toxic epidermal necrolysis need ongoing care for various long-term health problems.

Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.

Understanding hair follicles through various models can help develop new treatments for hair disorders.

Hairless protein affects hair follicle structure by regulating the Dlx3 gene.

A new small peptide may help hair growth by activating a specific receptor and should be tested in humans.

Cats lose fur due to various reasons, including allergies, infections, genetics, hormones, diet, cancer, stress, and some conditions are treatable while others are not.

Gene therapy in mice increased lifespan and improved health without causing cancer.

Tailored treatment plans are crucial for managing canine dermatomyositis-like disease.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.

Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.

Loss of OGG1 increases skin inflammation and auto-antibodies in lupus.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.

Changing the diet of mice lacking the enzyme CBS can affect symptoms related to the genetic condition.

N-acetyl-L-cysteine (NAC) can prevent DNA damage and protect cells from harm.

Scalp reduction surgery can effectively treat male pattern baldness when tailored to the patient and performed with care to minimize complications.

A mix of specific inhibitors and a growth factor helps keep hair growth cells from losing their properties in the lab.