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Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Edible seeds from the Cucurbitaceae family like pumpkin and watermelon seeds are nutritious and may have health benefits, but eating too much can cause side effects.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Women experience various skin issues at different life stages, requiring careful treatment and awareness.

Take care of your hair as much as your face for a youthful look.

PCOS is common, affects fertility, and requires personalized treatment to manage symptoms and health risks.

Women with the NIH type of PCOS have more obesity and higher risk of diabetes and heart disease than those with other types of PCOS.

Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

People with alopecia areata often have lower iron levels than healthy people.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

Serenoa repens (saw palmetto) may cause side effects like hot flashes in children and needs more research for safety in pediatric use.

The report recommends personalized treatment for women's sexual dysfunctions and more research on effective therapies.

The document concludes that different types of permanent hair loss conditions are related and early treatment is key to preventing further damage.

Mais estudos são necessários para garantir a eficácia e qualidade dos tratamentos de alopecia com plantas medicinais.

Low iron levels are strongly linked to chronic hair loss in women.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Women with PCOS have more severe liver disease.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.

Low testosterone in men is a risk factor for a specific heart rhythm issue, and testosterone treatment may help prevent it.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Women with hyperandrogenism have higher androgen levels and lower SHBG, which may contribute to conditions like excessive hair growth and early puberty.

Both estrogens and androgens are important for health in both males and females.

More men are getting cosmetic procedures, mainly for aging, hair loss, and to keep masculine features, with growing interest in both surgical and noninvasive treatments.

Obstetrician/gynecologists can diagnose and manage female hair loss with careful history taking and examination.

Phytotherapeutic compounds and supplements can help manage Polycystic Ovarian Syndrome (PCOS).

Use minoxidil for hair loss treatment; assess results after 6 months.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.