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    Glossary Post-Inflammatory Hyperpigmentation

    skin darkens after inflammation due to excess melanin production

    Post-Inflammatory Hyperpigmentation (PIH) is a condition where the skin becomes darker in color after an inflammatory event, such as acne, eczema, or a skin injury. This occurs because the inflammation triggers an overproduction of melanin, the pigment responsible for skin color, leading to dark spots or patches that can persist even after the initial inflammation has healed.

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    1. Q-switched Nd:YAG 1064-nm laser for the treatment of acne-induced postinflammatory hyperpigmentation Journal of The American Academy of Dermatology · 2009
    2. The Therapeutic and Preventive Effects of Light‐Emitting Diode (LED) for Post‐Inflammatory Erythema and Hyperpigmentation: A Pilot Study Photodermatology Photoimmunology & Photomedicine · 2025 · 1 citations
    3. Postinflammatory hyperpigmentation: a common but troubling condition International Journal of Dermatology · 2004 · 114 citations
    4. Solar-Induced Postinflammatory Hyperpigmentation after Laser Hair Removal Dermatologic surgery · 1999 · 31 citations
    5. 1927 nm Thulium Laser Successfully Treats PostInflammatory Hyperpigmentation in Skin of Color Dermatology Research and Practice · 2021 · 12 citations
    6. Intradermal Local Injection of Autologous Cell‐Free Fat Extract for the Treatment of Refractory Postinflammatory Hyperpigmentation Dermatologic Therapy · 2023 · 2 citations
    7. A Case of Folliculitis Decalvans With Concomitant Acne Keloidalis Nuchae, Androgenic Alopecia, and Profound Postinflammatory Hyperpigmentation Journal of the Dermatology Nurses’ Association · 2019
    8. A Case of Folliculitis Decalvans With Concomitant Acne Keloidalis Nuchae, Androgenic Alopecia, and Profound Postinflammatory Hyperpigmentation Journal of the Dermatology Nurses’ Association · 2019
    9. Fractional Resurfacing and Topical Bimatoprost for the Treatment of Laser Induced Postinflammatory Hypopigmentation on the Lower Extremities Dermatologic surgery · 2017 · 4 citations
    10. Skin Pigmentation Types, Causes and Treatment—A Review Molecules · 2023 · 138 citations
    11. A pilot study for triple combination therapy with a low-fluence 1064 nm Q-switched Nd:YAG laser, hydroquinone cream and oral tranexamic acid for recalcitrant Riehl’s Melanosis Journal of dermatological treatment · 2016 · 36 citations
    12. Fractional resurfacing in the Asian patient: Current state of the art Lasers in Surgery and Medicine · 2016 · 33 citations
    13. A Comprehensive Review on Skin Pigmentation-Types, Causes, and Treatment Preprints.org · 2023 · 32 citations
    14. Arabic version of Skindex‐16: Translation and cultural adaptation, with assessment of reliability and validity International Journal of Dermatology · 2007 · 24 citations
    15. Pseudofolliculitis barbae; current treatment options Clinical, cosmetic and investigational dermatology · 2019 · 21 citations
    16. Dermatotoxicology of microneedles (MNs) in man Biomedical Microdevices · 2019 · 19 citations
    17. Adverse events of non-ablative fractional laser photothermolysis: a retrospective study of 856 treatments in 362 patients Journal of Dermatological Treatment · 2013 · 18 citations
    18. Epidemiology of Cosmetic Procedures: An Update for Dermatologists Current Dermatology Reports · 2012 · 12 citations
    19. Chemical pharmacotherapy options for managing adult acne Expert Opinion on Pharmacotherapy · 2017 · 10 citations
    20. Updates in the understanding and treatments of skin & hair disorders in women of color International Journal of Women's Dermatology · 2015 · 10 citations
    21. Pseudofolliculitis barbae; current treatment options DOAJ (DOAJ: Directory of Open Access Journals) · 2019 · 5 citations
    22. Treatment of periorbital aging with negative pressure fractional microneedle radiofrequency: A self‐controlled clinical trial Journal of Cosmetic Dermatology · 2023 · 4 citations
    23. The impact of different hair‐removal behaviours on the biophysical and biochemical characteristics of female axillary skin International Journal of Cosmetic Science · 2020 · 4 citations
    24. Complications of radiofrequency microneedling: a comprehensive review BMC Plastic and Reconstructive Surgery · 2026 · 1 citations
    25. In Vitro Skin Models for Pigmentary Disorders: From Reconstructed Tissues to Skin-on-a-Chip Platforms Regenerative Biomaterials · 2026
    26. Perifollicular Elastolysis: A Systematic Review of Clinical Characteristics, Histopathology, and Therapeutic Outcomes Cosmetics · 2026
    27. Advancing the Understanding and Management of Segmental Vitiligo and Co‐Existing Pigmentary Disorders International Journal of Dermatology · 2025
    28. Clinical and Dermoscopic Evaluation of the Efficacy Melasma Treatment with Oral Tranexamic Acid 2023
    29. 604 Comparison of 1064-nm Nd:YAG picosecond lasers using fractional micro-lens array vs. ablative fractional 2940-nm Er:YAG lasers for the treatment of atrophic acne scar in Asians: A 20-week prospective, randomized, split-face, controlled trial Journal of Investigative Dermatology · 2023
    30. 34546 A topical antioxidant serum containing silymarin reduces sebum peroxidation and improves facial acne Journal of the American Academy of Dermatology · 2022