August 2025 in “مجلة جامعة الحضارة للبحوث التطبيقية والإنسانية” This study conducted in Yemen involving 50 patients found that tissue expansion was effective for correcting scars and defects from post-burn and post-war injuries, achieving a 78% satisfaction rate with minimal complications.
April 2023 in “The Egyptian Journal of Hospital Medicine” The study found that intralesional injection of platelet-rich plasma appears safe and may be effective for treating post-burn scars, with shorter scar durations showing better results.
Microneedling improves the appearance and feel of post-burn scars.
July 2022 in “The Egyptian Journal of Plastic and Reconstructive Surgery” This study concluded that using platelet-rich plasma in follicular unit extraction for post burn alopecia is beneficial, offering fewer hazards and complications, and a shorter recovery time compared to other hair restoration procedures.
January 2024 in “The Egyptian Journal of Plastic and Reconstructive Surgery” In this study, autologous fat injection was found to be more effective than platelet rich plasma in improving post-burn facial scars, as measured by decreased Vancouver scores and increased epidermal thickness among 60 patients.
July 2025 in “Russian Journal of Transplantology and Artificial Organs” This research highlights advancements in reconstructive surgery for managing scars, emphasizing the importance of combined surgical and nonsurgical interventions like platelet-rich plasma and stem cell therapy to prevent and treat thick scar tissue while enhancing functionality and aesthetic outcomes.
26 citations
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February 2011 in “Journal of Plastic Reconstructive and Aesthetic Surgery” Technique effectively treats deformities, achieves re-pigmentation, and releases scar contractures.
November 2025 in “Journal of Clinical Medicine” This study found that platelet-rich plasma may improve patient-reported outcomes for scar symptoms like pain and itching at six months, although no significant changes in scar appearance were observed at three months.
April 2024 in “Journal of burn care & research” This study found that neck defect size was more relevant than total body surface area for predicting contracture recurrence after burn injury, suggesting increased attention to defect size in managing such cases.
April 2024 in “Journal of burn care & research” This study found that most patients with burn scar alopecia chose to pursue multiple surgical treatments regardless of total body surface area affected or gender, highlighting the importance of personalized aesthetic goals in post-burn care.
14 citations
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May 2019 in “Journal of Maxillofacial and Oral Surgery” This article explains the FUE technique for hair transplantation, its associated risks and complications, and outlines a protocol for maxillofacial surgeons, but reports no new clinical results.
This review discusses recent advances in using stem cells for skin repair and regeneration after severe burn injuries, but it reports no new clinical results.
April 2023 in “Research Square (Research Square)” The researchers reported that combining stromal vascular fraction (SVF) with fractional CO2 laser treatment significantly improved burn scar outcomes and patient satisfaction compared to using the laser alone.
5 citations
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February 2024 in “Journal of Cosmetic Dermatology” This study found that FUE hair transplantation is effective for treating secondary scarring alopecia from burns, offering natural hair growth, quick recovery, high patient satisfaction, and few complications.
5 citations
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December 2018 in “Annals of plastic surgery” In this report, seven burn patients developed hypertrichosis after undergoing pressure garment/silicone therapy intended to prevent hypertrophic scarring.
June 2002 in “Surgery (oxford)” This review discusses the post-burn deformities seen after healing from acute burns and emphasizes the need for integrated, multidisciplinary management to prevent these sequelae; it reports no new clinical results.
1 citations
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December 2006 in “Burns” New therapies for burn wounds show promise in reducing pain, infection risk, and improving healing and physical outcomes.
November 2022 in “PubMed” This study found that inadequate thickness of deep dermal tissue in pigs is a key factor leading to fibrosis, with fibrosis likely serving a compensatory function for skin thickness.
2 citations
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September 2019 in “Dermatologic Surgery” This retrospective study observed that hair grafting in burn and postskin graft scars, which preserve deeper skin layers, had more favorable outcomes than in scars extending to the subcutaneous layer.
14 citations
,
May 2011 in “Physical medicine and rehabilitation clinics of North America” This article discusses the growing focus on long-term outcomes in burn care, emphasizing the importance of coordinated team approaches in burn reconstruction, but it presents no new clinical findings.
December 2016 in “Journal of Pakistan Association of Dermatology” In this study, tissue expansion was identified as a safer initial procedure before hair transplantation for patients with large scalp defects, with the majority of participants having postburn scars and a mean expansion time of 33.6 days.
79 citations
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January 2019 in “International Journal of Molecular Sciences” This study characterized the inflammatory response in a murine burn model, revealing similarities to human burns and supporting the model's use in testing therapies for burn complications.
26 citations
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July 2007 in “Wound Repair and Regeneration” This study found that MRL/MpJ mice heal burn wounds with scar formation, experiencing delayed wound closure and impaired myofibroblast development, which contrasts with quicker contraction in BALB/c mice.
January 2007 in “E-Deusto: conocimiento para ir por delante” This study characterized the inflammatory response in a promising murine model of thermal burns, similar to human burns, to inform future burn complication studies and preclinical testing of therapies.
3 citations
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October 2023 in “Plastic & Reconstructive Surgery Global Open” This study suggests that waiting for scarred tissue to mature and preparing the recipient area with nanofat can lead to better outcomes for hair transplantation in patients with eyebrow loss due to deep facial burns.
8 citations
,
January 2015 in “Scars, burns & healing” This review discusses surgical and non-surgical options for hair restoration in burn alopecia, highlighting follicular unit extraction and transplant as preferred methods but reports no new clinical findings.
2 citations
,
January 2017 in “Recent clinical techniques, results, and research in wounds” This study found that adding galeotomies to subgaleal tissue expander placement for post-burn alopecia resulted in faster scalp expansion and reduced complications of expander extrusion.
3 citations
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January 2012 in “Elsevier eBooks” Burn scars form abnormally due to changes in wound healing, and more research is needed to improve treatments.
10 citations
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January 2018 in “Elsevier eBooks” This review discusses the wound healing process and the factors contributing to abnormal scarring after thermal injuries, but it reports no new clinical results.
8 citations
,
May 2021 in “Applied Materials Today” This study found that Cur-Fe-mesoporous silica nanoparticles synergistically inhibited scar formation and promoted hair follicle regeneration in skin burn wound healing by releasing bioactive components like SiO32−, Fe3+, and Fe-Cur chelates.