42 citations
,
April 2009 in “Human Genetics” This study suggests that the AGA risk haplotype in Europeans was driven to high frequency by positive selection, likely associated with a variant in the EDA2R gene.
2 citations
,
April 2025 in “Frontiers in Genetics” This study investigated the genetic basis of coat color variation in cattle using skin transcriptome and whole-genome analyses, identifying the ASIP gene as a significant determinant that is differentially expressed and under strong positive selection in black and brown cattle breeds.
January 2006 in “Chieh P'ou Hsueh Pao” This study established a method for selecting human hair follicle stem cells through quick-adherence to collagen, and found that β-catenin plays a role in their proliferation and differentiation.
119 citations
,
August 2008 in “BMC Evolutionary Biology” This study found that while the KRTAP gene family is unique to mammals, humans have a similar number of these hair gene types as other primates despite having less body hair.
50 citations
,
February 2013 in “BMC evolutionary biology” This study found that the Hr gene loss and positive selection for the FGF5 gene in cetaceans likely contributed to hair loss as these animals adapted to aquatic environments.
9 citations
,
July 2011 in “Scientific Reports” This study suggests that human evolution involved accelerated changes in the HR gene, affecting its role in mediating postnatal hair cycling.
4 citations
,
December 2012 in “Human Biology” In this study, researchers found that two dominant haplotypes in the EDA2R/AR intergenic region have likely been shaped by demographic changes and selection during human evolution, particularly notable in African and non-African populations.
25 citations
,
March 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that while VDR is crucial for maintaining hair follicles in mice, their degeneration may be linked to impaired cell migration during hair growth phases rather than stem cell loss.
November 1999 in “Facial Plastic Surgery Clinics of North America” This article discusses the importance of selecting suitable candidates for surgical hair restoration to achieve positive outcomes and does not report new results.
April 1940 in “Archives of dermatology” This abstract presents a case of arsenical dermatitis with pigmentation and alopecia developed during treatment with arsphenamine for a positive Wassermann reaction.
30 citations
,
November 2019 in “Genetics selection evolution” This study found that in Chinese goat breeds, specific genetic variations, particularly in Tibetan Cashmere goats, are associated with traits like hair growth and adaptation to high-altitude environments.
November 2025 in “Journal of Kufa for Chemical Sciences” This study suggests that L-Selectin and adiponectin may be useful markers for distinguishing between Metformin-treated and untreated PCOS patients.
1 citations
,
July 2021 in “Frontiers in Oncology” This study found that patient-reported outcomes were similar between neoadjuvant endocrine therapy and chemotherapy in premenopausal breast cancer patients, but future perspective was significantly better with endocrine therapy.
3 citations
,
November 2023 in “Journal of Computer Science and Engineering (JCSE)” This study observed that using the Fisher score feature selection approach with capsule network models led to a promising 94% accuracy in diabetes detection, indicating its potential as a diagnostic tool.
June 2024 in “Journal of Cosmetic Dermatology” This study found that when choosing between hair transplant and scalp micropigmentation for female pattern hair loss, scalp micropigmentation is preferred if hair density is at least 104.6 hairs/cm².
January 2024 in “Journal of Natural Remedies” This study found that the petroleum ether extract of Solanum nigrum may promote hair regrowth in testosterone-induced hair loss in rats, as indicated by increased follicle density and anagen/telogen ratio.
May 2015 in “Hair transplant forum international” This article contains no research findings; it reports on an online discussion about platelet-rich plasma (PRP) and opinions shared during a conference.
7 citations
,
March 2011 in “Expert Opinion on Drug Safety” This review discusses the efficacy and safety of exemestane as a treatment for estrogen-receptor-positive breast cancer and reports no new clinical results.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers propose that the EDAR V370A allele's positive selection in East Asian populations may be linked to stable aquatic resources from Late Pleistocene ecosystems in northern China, suggesting a "nutritional niche construction" framework where these resources offset the allele's metabolic costs.
September 2022 in “Dermatologic Therapy” This study found that the U.S. stock market responded heterogeneously to the latest presidential elections, with positive reactions in the Energy, Financials, and Industrials sectors but poorer performance among firms with better environmental scores.
March 2024 in “Frontiers in genetics” This study used genomic analysis to reveal moderate genetic diversity, minimal inbreeding, and specific genes under positive selection in Xiangdong black goats, highlighting their unique adaptation traits and potential for breeding and conservation.
March 2024 in “Facial plastic surgery clinics of North America” This chapter reviews treatment options for androgenetic alopecia, noting FDA-approved finasteride and minoxidil for stabilizing or improving scalp coverage, positive off-label results with platelet-rich plasma, and effectiveness of hair transplantation using healthy follicular units.
January 2021 in “Global Dermatology” This study involved selecting patients with specific types of alopecia for treatment but does not report clinical outcomes.
January 2008 in “Zhongguo zuzhi gongcheng yanjiu yu linchuang kangfu” This study found that selecting human vaginal mucosa stem cells by adhesion to type Ⅳ collagen for 20 minutes and culturing them with feeder layer and epidermal total culture media was most effective in maintaining their characteristics.
October 2022 in “Portuguese journal of dermatology and venereology” This case study reports significant improvement in severe atopic dermatitis and alopecia areata symptoms in a patient treated with dupilumab, highlighting the potential for patient selection in optimizing therapeutic outcomes.
October 2022 in “Asian journal of healthy and science” This study found that a 20% concentration of mother-in-law's tongue leaf extract promoted hair growth in male rabbits, with effectiveness comparable to a positive control.
17 citations
,
March 2021 in “Expert Opinion on Biological Therapy” This review analyzes the impact of different preparation methods for platelet-rich plasma, human follicles stem cells, and adipose-derived stem cells on hair regrowth and wound healing, but reports no new results; the authors emphasize convincing evidence of positive outcomes despite protocol variability.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study presents a hypothesis that the EDAR V370A allele was positively selected in East Asian populations due to the stable aquatic resources in Late Pleistocene northern China, which may have offset the allele's metabolic costs and provided a selective advantage.
13 citations
,
July 2024 in “BMC Genomics” In this study, researchers found that single SNPs have a small genetic effect on phenotypes in Inner Mongolia cashmere goats, and constructing haplotypes from associated SNPs may uncover complex variations in cashmere traits, aiding genomics and breeding efforts.
3 citations
,
September 2023 in “Genes” This study analyzed the molecular evolution and functional divergence of the Dkk gene family, finding accelerated evolution in Aves and Reptilia and identifying functional differences that may impact hair follicle development via Wnt signaling inhibition.