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Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Skin fat cells help with skin balance, hair growth, and healing wounds.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

The new "differential stripping" method effectively measures how much substance gets into hair follicles.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Androgens, like testosterone, are crucial for early testicular descent in rats.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.

Particles around 100 nm can penetrate and stay in hair follicles without passing through healthy skin, making them safe for use in topical products and useful for targeted drug delivery.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Liposomes could improve how skin care products work but are costly and not very stable.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

Fullerenes show potential in skin care but need more safety research.

Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.

Researchers identified genes linked to coat color, body size, cashmere production, and high altitude adaptation in goats.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.

The document concludes that rapid identification, isolation, and strict infection control are crucial to manage SARS outbreaks.

Drugs penetrate scalp skin better than abdominal skin, with scalp hair follicles aiding in higher drug delivery.

PDRN helps repair tissue and improve wound healing with a high safety profile.

Chitosan nanoparticles improve minoxidil delivery to hair follicles for better alopecia treatment.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.

Toxic epidermal necrolysis is a severe skin condition often caused by drugs, with complex treatment and a high risk of death, but survivors usually heal without scars.