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Porcine skin cells are useful for studying wound healing and cancer.

In this study, clinically used preoperative skin preparations with povidone iodine and chlorhexidine gluconate did not meet FDA log-reduction standards for bacterial bioburden in a porcine model, suggesting persistent infection risks.

In this study, FITC-labeled BSA nanocarriers delivered a model drug deeper into porcine ear skin hair follicles than the carriers themselves, as shown by confocal microscopy.

This review discusses the immune functions of porcine skin and proposes a classification of dendritic cell subsets based on similarities to human skin, but it reports no new clinical results.

In a porcine model, this study observed that using an External Tissue Expansion Device increased epidermis thickness, cell proliferation, and vessel density at fat graft recipient sites.

This study found that low massage frequencies like 4.2 Hz enhance nanoparticle penetration into hair follicles more effectively than higher frequencies, indicating potential applications in therapeutic and cosmetic delivery.

This study compared porcine-derived placental biomaterials with human-derived counterparts in a rat model of skin injuries and found no significant statistical differences in healing outcomes; however, porcine-derived materials showed reduced early inflammation and faster crust formation, suggesting potential advantages in healing effectiveness.

In this study, penetration of FA-PLGA nanoparticles into hair follicles was observed in excised dog, rat, and porcine skin, with the deepest penetration in porcine skin, suggesting its similarity to human skin for drug delivery studies.

This study suggested that MRF may support skin regeneration and rejuvenation by promoting collagen synthesis and regulating factors involved in fibroblast activation and ECM remodeling, with preliminary findings indicating ADSCs might aid these processes.

This database provides detailed physiological parameters of porcine skin to enhance the MPML MechDermA Model, improving dermal absorption predictions for human studies in the Simcyp Simulator.

This study found that porcine ear skin is more suitable than excised human skin for investigating the efficacy of barrier emulsions in preventing pollen allergen penetration due to its lack of tissue contraction.

This study found that water-filtered infrared A radiation can induce the release of a model drug from gold nanoparticle-doped particles in hair follicles in an ex vivo porcine skin model, suggesting feasibility for follicular drug delivery systems.

In this study, using an ex vivo porcine skin model, researchers found that a 4% nanoparticle concentration significantly enhanced the transport of fluorescein sodium into hair follicles compared to a 2% concentration, while higher concentrations did not further increase penetration depth.

In this study, acellular dermal matrix hydrogels significantly improved healing in a rat model of radiation-induced skin injury by promoting angiogenesis and modulating inflammation, suggesting potential as a novel treatment for this common radiotherapy complication.

This study found that the hydrophilic PTK-UR foam with EG7 repeats significantly improved wound healing in porcine skin wounds compared to other scaffolds, suggesting potential for synthetic biomaterial applications.

This study found that mouse embryonic fibroblasts better supported the growth and maintenance of LGR5+ epidermal stem cells compared to porcine fetal fibroblasts, under various culture conditions.

This study found that rete ridge morphogenesis in mammalian skin is directed by a BMP-dependent developmental program, which is evolutionarily distinct from other known pathways controlling the development of hair follicles, sweat glands, and fingerprint ridges.

This research presents a comprehensive workflow for producing EMA-compliant autologous keratinocyte-based therapies for wound healing and explores miRNA-mediated regulations in human keratinocytes and adipose-derived mesenchymal stem cells.

This study used porcine models to isolate and culture stem cells from brain and hair follicles, shedding light on differentiation processes and potential markers for stem cell compartments under lab conditions.

This study found that porcine skin serves as a reliable model for studying drug absorption into human hair follicles, showing a strong correlation in follicular drug absorption between porcine and human skin.

This study reported that combining microdialysis and selective follicular closure with varnish significantly reduces caffeine penetration through hair follicles in an ex vivo porcine ear skin model.

In this study, researchers demonstrated that follicular tight junctions in porcine skin form a barrier to nanoparticle penetration, particularly in upper regions, which supports its use as a model for human skin.

In this study, hydrophilic EG7 PTK-UR foams promoted better wound healing and tissue integration in a porcine model compared to more hydrophobic PTK-UR variants and a polyester-based alternative, while matching a collagen-based standard.

This study reviews various skin models and methodologies used to assess the follicular penetration of nanoparticle-based drugs, highlighting inconsistencies that complicate comparisons and aims to establish more uniform protocols for clearer study outcomes.

This review compares animal and human skin characteristics in in vitro permeation studies but reports no new results, highlighting variations and the need for better model correlations.

This study found that using a protease-triggered release system enabled effective delivery of a model drug deep within porcine hair follicles, suggesting a new approach for treating skin conditions.

This study details the histological structure of the white domesticated pig's ear skin and discusses its relevance as a model for human dermatological research.

This study suggests that the hydrogel nanoparticle formulation of hair growth-promoting compounds may enhance hair follicle penetration and induce hair growth in tested models, demonstrating its potential as a hair growth treatment.

Liposomes with certain properties can effectively deliver drugs deep into hair follicles.

This study found that both allogeneic and xenogeneic small extracellular vesicles from adipose tissue similarly enhanced soft tissue regeneration and wound healing in rat models, implying similar therapeutic effects across species.