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August 2016 in “Journal of controlled release” Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
144 citations,
March 2013 in “Circulation Research” K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.
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August 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects” TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.
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December 2016 in “Molecules” Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.
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October 2013 in “Trends in Genetics” The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.
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December 2000 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” KGF and activin are crucial for skin healing and repair.
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August 2002 in “Journal of Neurology, Neurosurgery, and Psychiatry” Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.
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October 2016 in “Nanomedicine: Nanotechnology, Biology and Medicine” Fullerenes show potential in skin care but need more safety research.
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July 2014 in “Cold Spring Harbor Perspectives in Medicine” The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.
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December 2016 in “Scientific Reports” Researchers identified genes linked to coat color, body size, cashmere production, and high altitude adaptation in goats.
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January 1999 in “Physics in Medicine and Biology” Skin can be cooled quickly and safely during laser treatments to protect it without affecting deeper layers.
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July 2010 in “Tissue Engineering Part A” Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.
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January 2018 in “Biomaterials Science” Sericin hydrogels heal skin wounds well, regrowing hair and glands with less scarring.
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June 2020 in “Materials & Design” Sponge helps heal wounds faster with less inflammation and better skin/hair growth.
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February 2020 in “Journal of Translational Medicine” Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
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December 2016 in “Facial plastic surgery” Different types of facial fat affect aging and treatment outcomes; more research is needed to enhance anti-aging procedures.
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August 2013 in “International Journal of Cosmetic Science” Hair greying is caused by oxidative stress damaging hair follicles and melanocytes.
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June 2015 in “Aesthetic Plastic Surgery” Platelet preparations generally show positive effects on wound healing and facial rejuvenation, but more thorough research is needed to confirm their effectiveness.
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November 2020 in “Molecules” Conductive hydrogels show promise for medical uses like healing wounds and tissue regeneration but need improvements in safety and stability.
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July 2015 in “Journal of innovative optical health sciences/Journal of innovation in optical health science” Nanoparticles around 600-700 nm can effectively enter and stay in hair follicles for days, which may help in delivering drugs to specific cells.
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May 2008 in “Drug Discovery Today: Disease Mechanisms” Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.
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November 2012 in “Pharmaceutical research” Surface-modified nanoparticles mainly use non-follicular pathways to enhance skin permeation of ibuprofen and could improve treatment for inflammatory skin diseases.
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December 2001 in “Journal of Endocrinology/Journal of endocrinology” FLRG and follistatin have different roles in wound healing.
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June 2009 in “Biomaterials” Skin cell clumping for hair growth is improved by a protein called fibronectin, which helps cells stick and move better.
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January 2011 in “Journal of Biomedical Optics” Infrared and Raman imaging can non-destructively analyze hair structure and help diagnose hair conditions.
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May 2018 in “Nutrition and healthy aging” Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.
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May 2016 in “Proceedings of the National Academy of Sciences of the United States of America” Changes in keratin make hair follicles stiffer.
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August 2018 in “Scientific reports” Claudin-1 is important for the barrier function and growth of hair.
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November 2016 in “Pharmaceutics” The hair follicle pathway significantly affects how easily water-loving chemicals pass through the skin.