research The Disease Spectrum, Epidemiology, and Etiology of Toxic-Shock Syndrome
Toxic Shock Syndrome cases increased due to new factors, but decreased with public health measures and changes in tampon use.
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research Interventions for Nail Psoriasis
Some systemic treatments work for nail psoriasis but can have serious side effects.
research The Use of a Transscrotal Testosterone Delivery System in the Treatment of Patients with Weight Loss Related to Human Immunodeficiency Virus Infection
The transscrotal testosterone patch normalizes hormone levels in men with AIDS and weight loss but does not improve weight, body mass, or quality of life.
research Focus on Skin as a Possible Port of Entry for Solid Nanoparticles and the Toxicological Impact
Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.
research Design Strategies of Conductive Hydrogel for Biomedical Applications
Conductive hydrogels show promise for medical uses like healing wounds and tissue regeneration but need improvements in safety and stability.
research Treatment of MSCs with Wnt1a-Conditioned Medium Activates DP Cells and Promotes Hair Follicle Regrowth
Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.
research Delivery of Tissue-Targeted Scalpels: Opportunities and Challenges for In Vivo CRISPR/Cas-Based Genome Editing
Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.
research Nanotechnology in Dermatology
Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.
research Dermatosurgical Techniques for Repigmentation of Vitiligo
Surgical methods like suction blister grafting and split-thickness skin grafting are highly successful for vitiligo repigmentation, but choosing the right patients is crucial for success.
research What Should It Take to Describe a Substance or Product as 'Sperm-Safe'?
Products should be called 'sperm-safe' only after thorough, well-designed tests.
research Clinical Management of Patients with ASXL1 Mutations and Bohring-Opitz Syndrome, Emphasizing the Need for Wilms Tumor Surveillance
Patients with Bohring-Opitz syndrome and ASXL1 mutations need regular kidney ultrasounds to check for tumors.
research Engineering Pro-Regenerative Hydrogels for Scarless Wound Healing
Hydrogels could lead to better treatments for wound healing without scars.
research Absorption Sites of Orally Administered Drugs in the Small Intestine
Different factors affect where drugs are absorbed in the small intestine, which is important for effective medication use.
research Ablative Fractional Resurfacing in Topical Drug Delivery: An Update and Outlook
Ablative fractional resurfacing could improve how well topical drugs penetrate the skin, but more research is needed to fine-tune the method.
research Burn Reconstruction: The Problems, Techniques, and Applications
Burn reconstruction improves with new techniques, materials, and tissue engineering.
research Prolactin Delays Hair Regrowth in Mice
Prolactin slows down hair growth in mice.
research Percutaneous Absorption of Minoxidil in Humans
Minoxidil absorbs poorly through skin, with low risk of side effects at 1-2% concentration.
research Acute Cardiomyopathy Induced by the Vasodilating Antihypertensive Agent Minoxidil
Minoxidil can cause heart muscle damage in dogs.
research Spatiotemporal Control of CRISPR/Cas9 Gene Editing
The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.
research Synergistic Antibacterial Activity and Wound Healing Properties of Selenium-Chitosan-Mupirocin Nanohybrid System: An In Vivo Study on Rat Diabetic Staphylococcus Aureus Wound Infection Model
The nanohybrid system significantly improved wound healing and showed strong antibacterial activity.
research Nanoparticles in Wound Healing: From Hope to Routine
Nanoparticles show promise for better wound healing, but more research is needed to ensure safety and effectiveness.
research Toxic Epidermal Necrolysis
Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.
research Trichohyalin: Presence in the Granular Layer and Stratum Corneum of Normal Human Epidermis
Trichohyalin is also found in the outer layers of normal human skin.
research Ultrasound-Activated Particles as CRISPR/Cas9 Delivery System for Androgenic Alopecia Therapy
Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.
research Promotion of Homology-Directed DNA Repair by Polyamines
Polyamines help fix DNA damage accurately in cells.
research Enhanced Topical Delivery of Finasteride Using Glyceryl Monooleate-Based Liquid Crystalline Nanoparticles Stabilized by Cremophor Surfactants
Improved hair loss treatment using special particles and surfactants.
research The Pharmacology of Regenerative Medicine
Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.
research Inhibition of Human Steroid 5β-Reductase (AKR1D1) by Finasteride and Structure of the Enzyme-Inhibitor Complex
Finasteride helps treat hair loss and prostate enlargement by blocking a specific enzyme.
research Electrophysiological Mechanisms of Minoxidil Sulfate-Induced Vasodilation of Rabbit Portal Vein
The study explains how minoxidil sulfate causes vasodilation in rabbits by opening potassium channels and inhibiting calcium channels.
research Alleviation of Multidrug Resistance by Flavonoid and Non-Flavonoid Compounds in Breast, Lung, Colorectal, and Prostate Cancer
Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.