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This review highlights the potential of nanotechnology in enhancing the treatment of androgenetic alopecia by facilitating targeted drug delivery, improving drug stability, and increasing concentration at target sites, although clinical validation and scalable manufacturing are needed for practical implementation.

This study describes the development of microneedle array patches for finasteride that released the drug over 7 to 14 days in vitro, suggesting a potential alternative to oral treatments for long-term management of benign prostatic hyperplasia and androgenic alopecia.

This study found that cationic surfactant-based conditioning systems significantly improve hair combability by forming a stable low-friction film on hair surfaces, reducing friction and enhancing sensory performance compared to standard systems, as confirmed by both instrumental and sensory evaluations.

This study found that cationic surfactant-based conditioning systems significantly reduce friction on hair fibers, improving wet and dry combability by forming a stable film layer on the hair’s surface, as verified by both instrumental and sensory evaluations.

Transamidases are present in the epidermis but their exact role is unclear.

In this review, the authors highlight that emulgels, a combination of gel and emulsion, provide an effective topical drug delivery system for hydrophobic drugs, offering benefits like controlled release and versatility in treating various dermatological conditions.

This study found that washing hair with surfactants reduces the internal density of hair due to cuticle lifting, and suggests that a cuticle-sealing strategy can inhibit this effect and maintain hair homeostasis.

This review highlights cellulose-based materials' potential in skin disease treatments, emphasizing their smart, responsive design for various conditions, with insights into their roles in wound healing, infection prevention, and wearable monitoring.

This review discusses the role of extracellular vesicles in psoriasis pathogenesis and their potential as therapeutic agents or drug delivery systems, but it reports no new clinical findings.

In this review, an association was reported between early-onset androgenetic alopecia and several health conditions like obesity and cardiovascular disease, with genetic and therapeutic research ongoing to improve treatment.

In this study, researchers developed a long-lasting antibacterial coating for medical implants by anchoring silver nanoparticles onto polyamide surfaces, demonstrating potential to improve implant safety and effectiveness by reducing infection and inflammation.

This article reviews CRISPR/Cas system delivery methods for genome editing and highlights RNA's promise in non-viral in vivo applications but reports no new clinical results.

This review highlights the potential of nanotechnology-based formulations in hair care and treatment, emphasizing how these innovative materials can enhance the stability, efficacy, and safety of active compounds while addressing the limitations of conventional formulations.

This review discusses advances in nanomaterial-based wound dressings for infection control, highlighting their ability to detect and treat bacterial infections effectively, but reports no new clinical results.

This review summarizes recent progress in microneedle-based drug delivery systems and discusses their potential impact on cellular mechanisms and immunization signaling pathways, highlighting the need for further development in fabrication methods.

This review examines integrins as pharmacological targets, discussing current integrin-based therapies and emphasizing the need to understand integrin mechanisms for successful drug development, without reporting new clinical results.

This review discusses the mechanisms involved in wound healing and explores the potential of nanomaterials as a promising approach to managing chronic wounds, but reports no new clinical findings.

This review examines hydrogel microneedles for transdermal drug delivery, discussing their applications and challenges but reports no new clinical results.

This study reviewed the role of probiotics in dermatological disorders and suggests they may help treat or prevent inflammatory skin conditions by modulating the microbiota, potentially reducing the need for steroids and antibiotics, though further research is needed to confirm efficacy and safety.

This paper critically reviews recent advances in the use of keratin-based biomaterials, highlighting their potential applications in wound healing, drug delivery, and tissue regeneration due to their biocompatibility, biodegradability, and ability to support cell growth.

This study found that udenafil-treated adipose-derived stem cells accelerated hair growth in mice by enhancing stem cell activity and growth factor secretion through the ERK and NFκB pathways.

This article reviews recent developments in microneedles combining metallic elements and herbal compounds for wound healing, highlighting their benefits such as enhanced therapeutic efficacy and reduced toxicity, and offering a reference for future advancements in this technology.

This study summarizes the role and potential applications of stem cell exosomes in skin and bone healing, highlighting their regenerative capabilities and suggesting innovative delivery methods like nanoliposomes and hydrogels to improve bioavailability and therapeutic outcomes.

This review examines new formulations for delivering 5-α-reductase inhibitors to improve targeted drug delivery in androgenetic alopecia, but reports no new clinical results.

This paper reviews the development of transdermal drug delivery systems for skin diseases, from first to fourth generation, and highlights ongoing challenges and the importance of clinical trials, but provides no new clinical results.

This study reports on a zinc-coordinated tri-enzyme nanogel system (Zn@nGSC) that mimics natural enzymatic processes to enhance enzymatic activity and cascade efficiency, showing potential in wound healing, hyperglycemia treatment, and antibacterial effects in a murine model of post-pancreatectomy.

This review examines how incorporating various polymers and active ingredients into polyurethane dressings can enhance their properties and adaptability for better wound repair and regeneration, suggesting a promising direction for developing advanced functional dressings.

This review discusses various microneedle technologies for long-acting drug delivery, highlighting design considerations and challenges in bringing these minimally invasive devices to market, but it reports no new clinical results.

This review highlights advancements in nanotechnology-based treatments for androgenetic alopecia, noting that these strategies could improve targeting and modulation of hair follicle environments compared to traditional therapies like minoxidil and finasteride, but also emphasizes challenges around safety, manufacturing, and regulation.

This review synthesizes the latest advances in wound healing and scar management, exploring molecular mechanisms, therapeutic strategies, and providing an evidence-based comparison of topical agents like Dermatix Ultra and Contractubex for scar improvement, aimed at informing clinicians and patients in decision-making.