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    Glossary Polygonum multiflorum

    traditional Chinese herb, also known as Fo-Ti, used for hair health

    Polygonum multiflorum, commonly known as Fo-Ti or He Shou Wu, is a traditional Chinese medicinal herb reputed for its potential benefits in promoting hair growth and overall vitality. It is often used in herbal remedies to treat conditions like alopecia and is believed to restore hair color and strength, although scientific evidence supporting these claims is limited.

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    Research 30 of 617

    1. Polygonum multiflorum extract support hair growth by elongating anagen phase and abrogating the effect of androgen in cultured human dermal papilla cells BMC complementary medicine and therapies · 2020 · 15 citations
    2. Optimization and Characterization of TSG-Enriched Polygonum multiflorum Extract and Its Dual Mechanism Against Androgenetic Alopecia via 5α-Reductase Inhibition and Wnt/β-Catenin Activation International Journal of Molecular Sciences · 2026
    3. Topical application of Polygonum multiflorum extract induces hair growth of resting hair follicles through upregulating Shh and β-catenin expression in C57BL/6 mice Journal of Ethnopharmacology · 2011 · 91 citations
    4. Synergistic effects of Rhynchosia nulubilis and Polygonum multiflorum extract combination on cell proliferation via targeting IGFBP-1 & NT-3 and cytotoxicity suppression in testosterone-induced human dermal papilla cells PLoS ONE · 2025 · 2 citations
    5. <i>In vivo</i>hair growth-stimulating effect of medicinal plant extract on BALB/c nude mice Pharmaceutical Biology · 2015 · 15 citations
    6. Bio-Pulsed Stimulation Effectively Improves the Production of Avian Mesenchymal Stem Cell-Derived Extracellular Vesicles That Enhance the Bioactivity of Skin Fibroblasts and Hair Follicle Cells International journal of molecular sciences · 2022 · 3 citations
    7. Scalp Microbiota Dysbiosis in Seborrheic Alopecia and Restoration Following Herbal Extract Shampoo Intervention Microorganisms · 2026
    8. Intrinsic and Extrinsic Factors Associated with Hair Graying (Canities) and Therapeutic Potential of Plant Extracts and Phytochemicals Applied Sciences · 2024
    9. In vivo hair growth-promoting efficacies of herbal extracts and their cubosomal suspensions Journal of Industrial and Engineering Chemistry · 2013 · 25 citations
    10. Development Studies of Cuticle Drugs from Natural Resources. I. : Effects of Crude Drug Extracts on Hair Growth in Mice YAKUGAKU ZASSHI · 1988 · 12 citations
    11. The Clinical Study Using Oriental Medicine Extract on Male Pattern Hair Loss 대한의생명과학회지 · 2004 · 7 citations
    12. The Hair Growth Effect of Polygoni mulitiflori Radix Water Extracts in C57BL/6 Mice Daehan miyong hakoeji · 2010 · 1 citations
    13. Potential Natural Products Regulation of Molecular Signaling Pathway in Dermal Papilla Stem Cells Molecules · 2023
    14. Composite double-layer microneedle loaded with traditional Chinese medicine for the treatment of androgenic alopecia Medicine in novel technology and devices · 2023
    15. Edthnopharmacological Review of Medicinal Plants for the Treatment of Alopecia International Journal of Advanced Research in Science, Communication and Technology · 2023
    16. 천연추출물을 이용한 발모 및 두피 개선에 관한 연구 동향 아시안뷰티화장품학술지 · 2014
    17. Topically used herbal products for the treatment of hair loss: preclinical and clinical studies Archives of Dermatological Research · 2017 · 25 citations
    18. 5α-Reductase Inhibitory Components as Antiandrogens From Herbal Medicine Journal of acupuncture and meridian studies · 2010 · 19 citations
    19. 적하수오 에탄올 추출물의 melanin 합성 촉진효과 생명과학회지 · 2017
    20. Promotion effect of constituents from the root of Polygonum multiflorum on hair growth Bioorganic & Medicinal Chemistry Letters · 2013 · 51 citations
    21. Molecular mechanism of polygonum multiflorum in the treatment of androgenic alopecia: based on bioinformatics and molecular docking method DOAJ (DOAJ: Directory of Open Access Journals) · 2022
    22. C57BL/6 마우스에서 하수오 열수추출물의 육모촉진 효과 대한미용학회지 · 2010
    23. 보문 : 마우스에서 하수오 열수추출물이 발모관련 효소활성과 유전자 발현에 미치는 영향 대한미용학회지 · 2010
    24. Studies on the effects of medicinal plant extracts on the hair growth stimulation The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology · 2002 · 1 citations
    25. Latín cadurcum 'female genitals' and Hesychian Greek xá8veog `hog': is there any connection between the terms? Maia-rivista Di Letterature Classiche · 2006 · 1 citations
    26. Discrimination and Proper Use of Polygoni Multiflori Radix, Cynanchi Wilfordii Radix, and Cynanchi Auriculati Radix in Korea: A Descriptive Review Evidence-based Complementary and Alternative Medicine · 2015 · 7 citations
    27. Integrated chemometric fingerprints of antioxidant activities and HPLC–DAD–CL for assessing the quality of the processed roots of Polygonum multiflorum Thunb. (Heshouwu) Chinese Medicine · 2016 · 12 citations
    28. Effects of Polygoni Multiflori Radix on the Elastase, and Collagenase Activities and the Procollagen Synthesis in Hs68 Human Fibroblasts The Korea Journal of Herbology · 2014 · 2 citations
    29. Bioinspired engineering of Polygonum multiflorum root nanovesicles regulates dermal papilla cells in vitro and stimulates human hair follicle growth ex vivo Frontiers in Physiology · 2026
    30. Hair Growth Promotion Activity and Its Mechanism of<i>Polygonum multiflorum</i> Evidence-based Complementary and Alternative Medicine · 2015 · 24 citations