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This review covers various aspects of hair biology, pigmentation, and development, focusing on genetic and biochemical modulation of hair follicle components but reports no new findings.

This study introduced a pH-responsive polymeric wound dressing that enhances healing in chronic wounds by changing shape and drug delivery based on wound pH, achieving a 94.88% healing rate in diabetic mice by day 14.

This review summarizes how common polymorphisms in androgen and estrogen receptor genes may influence aging-related symptoms and diseases in men, but it reports no new clinical results.

This review discusses the use of zinc supplementation in dermatology for various skin conditions and reports no new clinical results, providing references for its application.

This review discusses the hormonal impact on hair growth and the relationship between endocrine disorders and hair changes, reporting no new clinical results.

This review discusses hydrogel-forming microneedles for non-invasive drug delivery in dermatology and reports no new clinical results, emphasizing their promise in improving treatment adherence and patient comfort.

This study highlights the potential of medicinal plants like Rubus vulgaris and Plantago major as sources for skin disorder treatments due to their bioactive compounds' antioxidant, anti-inflammatory, and antimicrobial effects.

This review discusses various nanotechnology-based strategies for managing melasma and reports no new clinical results, highlighting the potential of innovative drug delivery systems in treating hyperpigmentation.

This study found that bovine milk-derived exosomes (MEV-miRNAs) significantly increased hair follicle dermal papilla cell viability and up-regulated key WNT signaling components in human hair follicles, suggesting potential therapeutic benefits for androgenetic alopecia and telogen effluvium through modulation of hair growth pathways.

This study reviews lipid-based nanocosmeceuticals and reports that they enhance therapeutic effectiveness in dermatological applications by improving skin hydration, reducing wrinkles, and effectively managing conditions like psoriasis and eczema, though further large-scale trials and regulatory alignment are needed for clinical use.

This research highlights the crucial roles of B vitamins in metabolism, neurological processes, and DNA functions, and describes emerging therapies that enhance vitamin absorption and therapeutic potential.

Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.

This study found that a novel nutraceutical supplement improved hair growth and strength in subjects with hair thinning compared to placebo, without reported side effects.

This study proposes reclassifying PCOS into two distinct phenotypes based on androgen levels and suggests androgen supplementation may overcome IVF resistance in one group with advancing age.

In this study, melatonin-loaded Pickering emulsions stabilized by chitosan-dextran sulphate nanoparticles and enhanced with lecithin showed improved photostability, antioxidant activity, and follicular delivery in androgenic alopecia-affected rats, potentially rivaling commercial minoxidil for hair loss treatment.

Alopecia areata patients often have eczema, thyroid issues, vitamin-D deficiency, and anemia.

This study found that in men with high genetic risk factors for polycystic ovary syndrome, there was an associated increase in obesity, type 2 diabetes, coronary artery disease, and androgenic conditions, suggesting these genetic factors can act independently of ovarian function.

This review highlights recent advances in the design of nanocarrier systems for transdermal drug delivery, detailing their potential to improve treatment precision for dermatologic conditions despite challenges like formulation stability and scalability.

This study reports that optimal follicular penetration in nanocarrier-assisted drug delivery for skin diseases occurs with carrier sizes between 300 and 650 nm, while certain traditional medicine practices have shown effectiveness in treating skin conditions.

This review highlights advancements in nanotechnology-based treatments for androgenetic alopecia, noting that these strategies could improve targeting and modulation of hair follicle environments compared to traditional therapies like minoxidil and finasteride, but also emphasizes challenges around safety, manufacturing, and regulation.

This review discusses the role of nanocarrier systems, such as nanoemulsions and liposomes, in delivering antioxidants into the skin to counteract oxidative stress, highlighting recent advancements in topical antioxidant therapy through nanotechnology.

This study presents evidence suggesting that androgenetic alopecia is most likely inherited through a polygenic model, challenging the traditional view that it is caused by a simple Mendelian autosomal dominant gene.

This study found no significant genetic association between the 5α-reductase enzyme genes and male pattern baldness, suggesting a polygenic etiology rather than simple inheritance.

In this review, an association was reported between early-onset androgenetic alopecia and several health conditions like obesity and cardiovascular disease, with genetic and therapeutic research ongoing to improve treatment.

This paper reviews the development of transdermal drug delivery systems for skin diseases, from first to fourth generation, and highlights ongoing challenges and the importance of clinical trials, but provides no new clinical results.

This review highlights the potential of nanotechnology for hair follicle regeneration, focusing on strategies such as hair cycle modulation, progenitor cell stimulation, and wound-induced hair neogenesis, while also discussing regulatory challenges that may affect the development of these innovative approaches.

This review discusses nanoparticle-based wound-healing materials, detailing their benefits, limitations, and recent advancements, and emphasizes the need for further understanding to enhance therapeutic outcomes.

Early diagnosis and treatment of PCOS are crucial to reduce health risks and costs.

This study identified four genetic loci on chromosomes 6, 10, 16, and 18 that may contribute to susceptibility for alopecia areata and suggested shared genetic factors with psoriasis.

Alopecia areata is complex, with genetic and immune factors, and animal models are key for future treatment research.