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This review explores the potential for using exosomes in treating autoimmune skin diseases and promoting skin regeneration, highlighting current applications, delivery methods, and ongoing clinical trials while also identifying challenges and future research directions within dermatology.

This expert opinion article presents insights from dermatologists and aesthetic physicians on using polynucleotides (Rejuran®) for skin hydration, rejuvenation, structural support, barrier repair, and scar remodeling, noting their favorable safety profile but highlighting the need for more robust evidence and research.

This guideline review by the European Dermatology Forum evaluates current treatments for androgenetic alopecia but reports no new research findings, aiming to assist dermatologists in selecting safe and effective therapies.

This review discusses the development and potential therapeutic applications of adenosine receptor agonists and positive allosteric modulators, noting that while many clinical trials have been unsuccessful, initial results for new compounds are promising.

This study reports that plasma rich in growth factors appeared to improve hair follicle regeneration and patient satisfaction in individuals with androgenetic alopecia, though further trials are needed.

This article discusses treatments for female pattern hair loss, highlighting that oral antiandrogens and topical minoxidil can effectively arrest progression and reverse miniaturization in many patients with mild-to-moderate cases, but it reports no new clinical results.

This meta-analysis suggests that local injection of platelet-rich plasma for androgenic alopecia is associated with an increased number of hairs and some increase in hair thickness, though larger studies are needed for confirmation.

This analysis suggests that platelet-rich plasma therapy may be promising for treating androgenetic alopecia, but further controlled trials with standardized measures are needed to confirm its efficacy.

This review discusses the varied use and inconsistent reporting of platelet rich plasma in aesthetic surgery, finding that current studies lack consistent methodologies and objective evidence, and reports no new clinical results.

This review discusses the diverse applications of platelet-rich plasma in aesthetic dermatology and assesses the existing literature on its effectiveness, reporting no new clinical results.

This review discusses female androgenetic alopecia, highlighting its diagnostic challenges and management strategies, but it reports no new results.

This review analyzed clinical trial protocols for platelet-rich plasma preparation in hair loss treatment, finding inconsistent and insufficient reporting that complicates comparison and efficacy determination.

This review found that three monthly PRP injections improved hair density in patients with androgenetic alopecia compared to placebo, but more rigorous studies are needed for broader dermatological applications.

This meta-analysis reported that platelet-rich plasma injections for androgenetic alopecia may increase hair number and thickness locally, but further studies are needed to establish their overall effectiveness.

This study found that platelet-rich plasma injections improved hair density and diameter in women with androgenetic alopecia not responding to other treatments over 24 weeks, with no adverse events reported.

This review suggests that PRP injections may be effective in promoting hair regrowth, reducing hair loss, and increasing hair thickness in patients with androgenic alopecia.

This review found that the current evidence on using platelet rich plasma to treat non-cicatricial alopecia, such as androgenetic alopecia and alopecia areata, is of low quality and yields controversial results.

This review detailed the types and mechanisms of injectable "skin boosters" and evaluated their effectiveness and safety for mitigating age-related skin changes, providing insight into their use in contemporary dermatological practice.

This research review found that platelet-rich plasma treatment generally produced successful hair regrowth in both androgenetic alopecia and alopecia areata, despite study differences that limited direct statistical comparison.

This study found that the CXXC5 protein is overexpressed in diabetic foot ulcer tissues, suppressing wound healing, and that the small molecule KY19334 accelerated healing in diabetic mice by activating the Wnt/β-catenin pathway.

This study found that autologous platelet-rich plasma was associated with increased hair density in people with pattern hair loss, but with considerable variability and unclear risks of bias.

This research highlights a hydrogel system that could significantly improve diabetic wound healing by releasing ibuprofen to both suppress inflammation and promote tissue regeneration, indicating a strong potential for future clinical use.

This review discusses the use of platelet-rich plasma for treating female androgenetic alopecia, reporting that it shows high patient satisfaction and improved quality of life in affected women.

In this study, researchers aimed to investigate the effects of injecting intralesional platelet-rich plasma and vitamin D in patients with vitiligo, focusing on their potential to induce skin pigmentation. Results are not reported in the abstract.

This study found that hairline lowering surgery using a bone tunneling technique without Endotine effectively reduced forehead length and achieved high patient satisfaction among 91 participants, with results sustained over 12 months and minimal reported complications.

This review discusses the impact of age-related hair changes on perceived attractiveness and self-perception, emphasizing the need for holistic anti-aging consultations that include hair preservation strategies.

This literature review suggests that fractional laser therapies may positively impact hair regrowth in androgenic alopecia, though current evidence is mostly limited to small studies and case reports, highlighting a need for more comprehensive randomized controlled trials to confirm their efficacy and safety.

In this study, subcutaneous platelet-rich plasma injections improved hair density and histological markers of hair growth in hairless rats without causing local toxicity.

This review outlines the biological effects of various placental extracts, noting their reported antioxidant, anti-inflammatory, and immunomodulatory activities, but highlights that the relationship between these effects and the extracts' specific contents remains unclear.

In this study, the TRICHOBIOLIGHT protocol showed effectiveness in treating androgenetic alopecia and telogen effluvium, with 82.5% of 103 patients experiencing excellent to good outcomes after mesotherapy and LED photobiostimulation on the scalp.