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The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Androgen use may increase the risk of stroke, but more research is needed.

The document concludes that respectful, gender-affirming healthcare improves mental health and encourages continued medical care for transgender and non-binary individuals.

Dermatologists are essential in helping transgender and gender diverse patients with skin and hair issues related to gender affirmation and hormone therapy.

A woman with Budd-Chiari syndrome improved after treatment and needs a liver transplant, highlighting the importance of considering non-criteria antiphospholipid syndrome in similar cases.

People in palliative care often have skin problems due to their main illness or other health issues, and treatments focus on comfort and quality of life.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

A woman's ovarian fibroma caused high testosterone levels, which normalized after surgery.

The study concluded that Acral lick dermatitis is most common in young male Labrador retrievers, often caused by psychological factors, and leads to skin inflammation and stress-related blood changes.

Surgical removal of a rare ovarian tumor improved symptoms and hormone levels in a postmenopausal woman.

Testosterone treatment for older men can have short-term benefits, but long-term risks are unclear, requiring careful evaluation and monitoring.

Treatment restored normal sexual characteristics and blood condition in a patient with testicular cancer.

A man with vitiligo and alopecia saw quick skin and hair improvement with ruxolitinib, but skin color gains were lost after stopping treatment.

Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.

JAK inhibitors show promise for treating skin and hair disorders but need more research on long-term safety and effectiveness.

Testosterone therapy can improve sexual function in women but long-term safety is unclear.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

Rosacea is a skin condition with unclear causes, classified into four subtypes.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

JAK inhibitors help with skin conditions but need more research on dosing and safety.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

New treatments for male hypogonadism are effective and should be personalized.