11 citations
,
September 2021 in “American Journal of Medical Genetics Part A” This study reports that newly diagnosed patients with Bachmann-Bupp syndrome exhibit a broader phenotype than previously documented, including late-onset seizures, and suggests a possible universal biochemical mechanism involving elevated ODC activity.
January 2015 in “CU Scholar (University of Colorado Boulder)” This research found that Foxc1 is critical for maintaining quiescence in activated hair follicle stem cells and that the cancer cell-of-origin influences tumor heterogeneity in mouse skin squamous cell carcinoma.
2 citations
,
November 2017 in “Histochemistry and Cell Biology” This study observed varying levels of polyamines in different compartments of rat hair follicles, indicating their potential involvement in hair growth, especially in the matrix and inner root sheath layers.
2 citations
,
May 2006 in “Journal of Separation Science” This study describes a capillary GC method for accurately measuring spermidine levels in hair lotions, confirming its precision and specificity for this application.
2 citations
,
September 1980 in “Experientia” Polyethylene alanine caused hair loss in young lab animals but not in adults, with hair regrowth occurring within 20 days.
200 citations
,
March 2023 in “Nature Reviews Molecular Cell Biology” This review discusses the role and regulation of quiescent adult stem cells in tissue maintenance and repair, focusing on molecular mechanisms and their implications for regenerative medicine, but reports no new clinical results.
8 citations
,
October 2017 in “Dermatology practical & conceptual” This study found that a spermidine-based nutritional supplement increased the number of anagen phase hair follicles in healthy humans, suggesting potential benefits for hair loss conditions.
January 2025 in “MEDS Public Health and Preventive Medicine” In this study, oral spermidine supplementation was found to significantly prolong the hair follicle anagen phase and reduce hair loss, with effects persisting three months after treatment in healthy participants, suggesting potential therapeutic benefits for hair loss conditions.
April 1978 in “Pediatric research” This study found that zinc levels in hospitalized patients with significant weight loss did not correlate with taste perception or vitamin A status, even in those with reduced taste acuity.
150 citations
,
June 2014 in “Biomaterials” This study found that 'smart' peptide hydrogels improved wound healing in a rat model of partial thickness burns, achieving greater wound closure and faster debridement compared to a standard treatment.
10 citations
,
January 2010 in “International Journal of Trichology” This article reviews the use of artificial hair fibers, discussing their controversial history and the FDA ban, and reports no new research findings.
4 citations
,
February 2020 in “Journal of Cosmetic Dermatology” This study reported significant moderate-to-severe complications in two patients following synthetic hair fiber implantation, including recurrent infections, scalp issues, and granulomatous reactions, which were only resolved once the fibers were removed despite initial treatment attempts with antibiotics.
3 citations
,
January 2018 in “Open Access Macedonian Journal of Medical Sciences” In this study, the use of Biofibre hair implants showed significant improvements in scalp coverage and Hamilton scale grading for 97.94% of male and female patients with androgenetic alopecia after two years, with minimal and manageable side effects reported.
115 citations
,
January 2001 in “American journal of clinical dermatology” This study found that eflornithine 15% cream reduced unwanted facial hair growth more effectively than a placebo in women with hirsutism, but hair growth returned to pretreatment levels within 8 weeks of stopping treatment.
77 citations
,
January 1980 in “Carcinogenesis” This study found that TPA was significantly more effective than mezerein in inducing dark basal keratinocytes in mouse skin, which may be important in early tumor promotion stages.
75 citations
,
January 2014 in “Archiv Der Pharmazie” This review discusses the synthesis and biological activities of jasmonates, highlighting their potential as drugs and prodrugs, but reports no new clinical results; further research and trials are anticipated.
29 citations
,
March 1983 in “Journal of The American Academy of Dermatology” This article reviews existing and emerging treatments for psoriasis, focusing on therapy modifications due to scientific advancements, but it does not report new clinical results.
26 citations
,
February 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that cutaneous pyridoxal 5'-phosphate hydrolase activity may be carried out by an enzyme different from the classical tissue-nonspecific alkaline phosphatase in human and mouse skin.
5 citations
,
March 2005 in “Journal of The American Academy of Dermatology”
2 citations
,
January 2014 in “Hair therapy & transplantation” This review explores the molecular controls of hair follicle cycling and highlights the challenge of developing effective treatments for common hair disorders without providing new clinical results.
1 citations
,
September 2019 in “Journal of Investigative Dermatology” In this study, researchers used a CRISPR-based method to correct mutations in the COL7A1 gene in stem cells from RDEB patients, restoring normal collagen expression in engineered skin grafts in mice.
September 2019 in “Journal of Investigative Dermatology” This study suggests that subtle modifications in ribosomal RNA methylation may influence cellular physiology and contribute to ribosome specialization in senescent human dermal fibroblasts.
February 2019 in “Journal of Pakistan Association of Dermatologists” In this study, eflornithine cream combined with intense pulsed light treatment significantly improved facial hair removal in women with hirsutism compared to IPL treatment alone.
June 2020 in “Journal of Investigative Dermatology” This study found that platelet-derived growth factor secretion in PRP therapy for alopecia is highly variable between patients, which may contribute to inconsistent clinical responses.
This review discusses recent advances in polydopamine-based biomaterials and their growing potential in personalized medicine, but reports no new experimental results; the authors highlight both opportunities and challenges for future applications.
165 citations
,
September 2001 in “Genes & development” This study found that Cutl1 mutant mice experienced retarded lung differentiation and abnormal hair follicle morphogenesis, indicating the vital role of CDP in lung development and hair follicle cell-lineage specification.
24 citations
,
July 1994 in “Molecular Endocrinology” Researchers found an RNA transcript that might help control a growth factor linked to tumor development.
5 citations
,
August 2013 in “InTech eBooks” This article reviews the role of KLF4, a transcription factor, in various cellular processes and its dual function as a tumor suppressor or oncogene depending on the context, but presents no new experimental results.
421 citations
,
January 2015 in “Chemical Society Reviews” This review discusses recent advances in surface modification and endothelialization of biomaterials for vascular grafts, highlighting promising methods like gene engineering and targeting ligand immobilization to improve clinical outcomes.
70 citations
,
August 2020 in “Nanomaterials” This review discusses the development of electrospun nanofibrous scaffolds for promoting angiogenesis in tissue engineering but notes that their clinical application beyond bone and skin repair is still limited.