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The document concludes that non-binary individuals need compassionate support and recognition in healthcare, without being pathologized.

Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

Polycystic ovary syndrome costs the U.S. over $4 billion a year, mainly from treating related health issues.

Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

Hair and nail cells share similar proteins, indicating a common differentiation pathway.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.

Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

PCOS is common among Chinese women of reproductive age and linked to serious metabolic and reproductive issues, especially in obese women.

The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.

Zinc oxide nanoparticles in sunscreen do not penetrate deep into the skin.

Medium-sized particles penetrate hair follicles better than smaller or larger ones, which could improve delivery of skin treatments.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.

The report recommends personalized treatment for women's sexual dysfunctions and more research on effective therapies.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Acne affects most teenagers and can continue into adulthood, with various treatments available that show improvement but have concerns like antibiotic resistance and side effects.

Hair loss in women is genetic, diagnosed by examination and biopsy, and treated with minoxidil, finasteride, or transplantation.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.