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The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

Noggin is necessary to start the hair growth phase in skin after birth.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

KGF and activin are crucial for skin healing and repair.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.

The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.

Minoxidil effectively controls blood pressure in severe cases, but has serious side effects and causes hair growth in women.

Liposomes better deliver minoxidil for hair loss treatment than niosomes.

Hair mineral analysis might help diagnose diseases early, but standard methods are needed.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Manatee whiskers are specially adapted for touch in water.

Lymphatic vessels are essential for hair follicle growth and skin regeneration.

Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Permanent hair dye damages hair but it mostly recovers after 8 weeks; using certain hair care products can help repair it.

Rituximab leads to longer remission and fewer side effects than cyclophosphamide.

Microneedles help treat hair loss by improving hair surroundings and promoting growth.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Patient had scalp allergy from minoxidil; test helped identify cause and suggest alternative treatments.