478 citations
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September 1996 in “Proceedings of the National Academy of Sciences” This study found that overexpression of PTHrP in mice chondrocytes led to short-limbed dwarfism and delays in endochondral ossification, highlighting PTHrP's role in inhibiting chondrocyte differentiation.
419 citations
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March 2005 in “Proceedings of the National Academy of Sciences” This study demonstrated that ND-GFP stem cells from the hair-follicle bulge area can differentiate into various cell types, including neurons, suggesting their potential as a source for therapeutic applications.
115 citations
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November 2008 in “Proceedings of the National Academy of Sciences” In this study, the researchers found that mammalian hair likely evolved through the adaptation of existing structural proteins, as similar cysteine-rich α-keratins were identified in chicken and lizard genomes, suggesting pre-mammalian origins.
103 citations
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February 1972 in “Proceedings of the National Academy of Sciences” This study found that a unique transglutaminase in guinea pig hair-follicles, distinct from liver transglutaminase, likely plays a role in forming protein cross-links via ε(γ-glutamyl)lysine bonds.
82 citations
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May 2010 in “PLoS neglected tropical diseases” This study provides quantitative evidence that secondary syphilis is highly endemic in Cali, Colombia, and many untreated patients have high numbers of circulating Treponema pallidum spirochetes.
46 citations
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May 1995 in “Proceedings of the National Academy of Sciences” This study demonstrated that a specific 9-kbp fragment of the bovine keratin 6 gene effectively directs tissue-specific and inducible expression in transgenic mice, suggesting potential applications for targeted gene therapy in hyperproliferative skin conditions.
41 citations
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March 2017 in “PLoS neglected tropical diseases” This study found that isotretinoin, a drug commonly used for acne, inhibits polyamine transport in Trypanosoma cruzi, leading to trypanocidal effects, and suggests its potential as a treatment for Chagas disease without affecting mammalian cell viability.
32 citations
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April 2013 in “Anais Brasileiros de Dermatologia” This article reviews the diagnosis and management of inherited epidermolysis bullosa and reports no new clinical findings; it emphasizes the importance of clinical and histopathological evaluation.
23 citations
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July 2023 in “Proceedings of the National Academy of Sciences” In this study using a mouse model and human data, researchers found that CD8+ T cells are central to driving alopecia areata, while regulatory T cells offer some protection, highlighting CD8+ T cells as key targets for future therapy development.
3 citations
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May 2011 in “Practice nursing” As skin ages, it gets thinner, paler, and more wrinkled, and protection and care like sunblock and moisturizers are important.
1 citations
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September 2021 in “Physiology News” The abstract did not include specific study details, results, or conclusions; therefore, it remains unclear what this research aimed to investigate or reported.
1 citations
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September 2021 in “Physiology News” The abstract contains only graphic design specifications and reports no new research findings.
1 citations
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March 2024 in “Psychiatry Neurology and Medical Psychology” This study examined the mental health of women with diffuse alopecia and found varied levels of mental maladjustment, with more patients with mixed alopecia showing adjustment disorders compared to those with metabolic alopecia. These findings could inform personalized treatment strategies for this condition.
1 citations
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January 2014 in “Progress in Neurology and Psychiatry” This report discusses the complex interplay between dermatological and psychiatric conditions and presents insights shared at the 22nd EADV Congress, but it reports no new research results.
November 2025 in “Practical Neurology” In this case report, a 31-year-old woman with severe multisystem lupus vasculitis initially presented with generalized pain and rapidly worsening neuropathy, ultimately improving with cyclophosphamide and prednisolone treatment. The authors highlight diagnostic challenges, particularly in interpreting autoantibody results after IVIG therapy.
May 2024 in “Psychiatric News” In this study, analysis of electronic health records suggested that patients taking semaglutide were significantly less likely to experience suicidal ideation compared to those on non-GLP-1 obesity or diabetes medications.
September 2021 in “Physiology News” This abstract lacks findings or results and does not provide a summary about any specific research study or topic.
September 2021 in “Physiology News” This abstract provides template specifications for design materials but reports no new research findings.
September 2021 in “Physiology News” This abstract contains no specific research findings or conclusions to summarize for a TLDR.
September 2021 in “Physiology News” The abstract does not provide any research findings or conclusions to summarize, focusing instead on color and logo specifications.
September 2021 in “Physiology News” This abstract contains only graphical design information and does not report any research findings or conclusions.
September 2021 in “Physiology News” The abstract does not provide any research findings or conclusions to summarize, focusing instead on color and logo specifications.
September 2021 in “Physiology News” This abstract provides no research results; it includes only formatting instructions and placeholders without scientific information.
September 2021 in “Physiology News” This abstract only contains a stylized text design and provides no research findings or clinical results.
September 2021 in “Physiology News” This abstract lacks specific study results and appears to contain a placeholder text or design template instead of research findings.
September 2021 in “Physiology News” This abstract provides visual branding guidelines for a logo, but contains no research findings or discussion.
September 2021 in “Physiology News” This abstract contains only graphical design information and does not report any research findings or conclusions.
September 2021 in “Physiology News” This abstract provides formatting and branding guidelines for logos, but reports no scientific findings.
May 2017 in “Psychiatric news” This study found that seniors using finasteride or dutasteride for benign prostatic hyperplasia may have an increased risk of depression and self-harm, especially during the first 18 months of treatment.
May 2011 in “Psychiatric News” This article provides regulatory updates, legal briefs, and industry news, reporting no new clinical findings.