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This study introduced a novel in vitro assay for tracking melanosome transfer between melanocytes and keratinocytes, facilitating the quantification of melanin transfer and supporting the role of filopodia as a conduit.

This study found that dual inhibition of BACE1 and BACE2 in mice affects melanosome maturation and causes dose-dependent hair depigmentation without altering retinal morphology.

This study found that a novel hydrogel scaffold, cGEL, significantly increased melanin production and melanotic gene expression in human melanocytes compared to other graft materials, suggesting its potential as a superior carrier for skin grafting.

This study found that Swiss cattle exhibiting rat-tail syndrome are heterozygous for genetic variants linked to pigmentation and color dilution, likely due to Holstein introgression in the Simmental breed.

This study found that transfecting alpaca melanocytes with miR-5110 altered gene expression related to pigmentation, specifically identifying pathways like MAPK and Wnt as involved in melanogenesis regulation, providing insights into miR-5110's role in pigmentation processes.

This study found that treating human skin explants with TPA increased the number of certain melanocyte phenotypes in the interfollicular epidermis, suggesting that this ex vivo model can effectively replicate human skin's pharmacologic responses for studying potential treatments.

This study identified specific genes that are more abundantly expressed in black hair than in gray hair, with black hair displaying higher expression of pigment-related proteins and gray hair showing increased expression of keratin-related genes.

This study explored the expression and potential functions of long non-coding RNAs in the skin pigmentation of Koi carp, revealing their involvement in pigmentation and differentiation mechanisms.

In this study, melatonin-loaded Pickering emulsions stabilized by chitosan-dextran sulphate nanoparticles and enhanced with lecithin showed improved photostability, antioxidant activity, and follicular delivery in androgenic alopecia-affected rats, potentially rivaling commercial minoxidil for hair loss treatment.

This study developed a new melanocyte cultivation medium without chemical mitogens, melanogenesis enhancers, or bovine products, demonstrating successful proliferation and melanotic differentiation of human melanocytes from hair follicles.

In this study, researchers found that exosomes derived from Pinctada martensii mucus can effectively inhibit melanin production in melanoma cells and zebrafish without adverse effects, potentially offering a promising therapeutic strategy for treating pigmentary disorders by modulating the NF-κB signaling pathway.

This review discusses the biology and development of skin melanocytes, but reports no new clinical findings.

In this study of a TRPS type I patient, many genes related to keratin and hair development were down-regulated in balding scalp areas, providing new insights into TRPS and hair morphogenesis.

This paper provides a comprehensive review of melanocytes' roles in skin biology, focusing on their pigmentation and immune functions, and suggests potential research opportunities for preventing and treating skin disorders.

In this study, the researchers developed a new protocol using human-induced pluripotent stem cells to efficiently create skin hair follicle organoids, which may aid in optimizing hair follicle growth and exploring treatments for alopecia.

In this study of four Chinese goat breeds, black goats exhibited significantly higher melanin content, while Inner Mongolian cashmere goats had longer fiber lengths. These findings highlight genetic variations in coat color and fiber length, informing future breeding programs.

This study found that a melatonin-loaded microemulsion exhibited controlled release and significant stratum corneum deposition in ex vivo permeation tests, suggesting its potential for further evaluation in treating androgenic alopecia.

This animal study observed that while topical MBEH and intraperitoneal phenol induced hair graying in eumelanic mice, they had little effect on pheomelanic mice, and amcinonide reduced certain epidermal melanocytes in both.

This review discusses the current research and development of mannosylerythritol lipids, particularly focusing on their potential commercial applications in cosmetics; it reports no new results.

This article discusses the clinical presentation, histopathologic findings, and pathogenesis hypotheses of vitiligo without reporting new clinical results.

This review examines recent advancements in electrospun nanofibers for wound healing applications, but reports no new experimental results, highlighting their potential in sutures, dressings, and skin regeneration.

This study highlights that niosomes, or non-ionic surfactant based vesicles, offer an advantageous drug delivery system due to their stability, cost-effectiveness, and ability to enhance drug bioavailability and targeting efficiency for various therapeutic agents.

This review discusses the identification and characteristics of melanocyte stem cells, emphasizing their role in hair pigmentation, greying, and skin repigmentation, but reports no new research findings.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

This study observed that applying JAK-STAT pathway inhibitors to mouse and human skin led to rapid hair growth by inducing the anagen phase of hair follicles.

This review summarizes the anatomical and physiological aspects of human hair and its clinical significance, but does not report new research findings.

This review examines current knowledge on human epithelial hair follicle stem cells, their markers, and outlines challenges in translating findings from murine studies to human research, but does not report new experimental results.

This review discusses melanocyte biology and its genetic and molecular basis, highlighting its relevance in understanding diseases like vitiligo and albinism, and reports no new findings.

In this study, researchers identified that upon tissue injury in a mouse model, epidermal cells at the wound edge convert to an embryonic-like state with SOX11 and SOX4 playing a central role in modulating epidermal development and cell migration genes.

This review examines cell senescence pathways in melanocytes, highlighting the involvement of telomere attrition, the p16/RB pathway, and cAMP signaling in the context of melanoma development, but reports no new findings.