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This study evaluated nanovesicles derived from Polygonum multiflorum roots, finding that they promote dermal papilla cell proliferation and activate β-catenin signaling, which in turn enhances hair shaft elongation in ex vivo cultured human hair follicles, suggesting their potential use for alopecia treatment.

This study found that double transgenic Arabidopsis plants overexpressing both AVP1 and AtNHX1 showed improved salt tolerance and enhanced root hair and hypocotyl growth compared to single transgenic lines.

This study reports a semidominant inheritance of epidermolytic ichthyosis due to a KRT1 mutation, which was previously thought to be only inherited dominantly.

This study found that shallot extract may promote hair growth in androgenetic alopecia by reducing inflammation and modulating gene expression related to key hair growth pathways.

This study found that Pep-1-mediated mitochondrial transplantation was as effective as PRP therapy in restoring hair loss related to aging in mice, with distinct improvements in hair and skin-related measures.

This study found that high concentrations of supplemental cobalt inhibited hair follicle development in rabbits, potentially involving the mTOR-BMP signaling pathway.

In this review, various expression systems for synthesizing recombinant collagen are compared, highlighting their efficiency, modification capabilities, and cost. Key purification techniques are also analyzed, and challenges like reducing R&D costs and improving safety protocols are identified.

In this study, subthermal RF-CRET currents were found to alter key molecular mechanisms in dermal papilla cells, promoting proliferation and survival while enhancing markers associated with hair growth and maintenance, suggesting potential benefits for hair regeneration.

This study found that electronically-operated pneumatic injections for administering a peptide-hyaluronic acid combination were well tolerated and led to significant improvement in hair density and thickness for men with androgenic alopecia over six months, though the exact mechanism remains uncertain.

This study found that foot shock stress prolonged the telogen stage and delayed anagen induction in the hair cycle of non-depilated mice, potentially through stress-induced actions of substance P.

This study found that the alcohol extract of Vernonia anthelmintica may counteract stress-induced hair follicle growth inhibition in mice, potentially offering a new approach for treating stress-related hair loss.

This review discusses neural mechanisms involved in hair growth control, focusing on piloneural interactions, but reports no clinical findings; the authors suggest further exploration for managing hair growth disorders.

This study found that the sebum partition coefficient (K(sebum)) for some drugs differs from the stratum corneum partition coefficient (K(sc)), indicating its importance for targeted drug delivery into hair and sebaceous follicles.

This study found that transgenic cashmere goats overexpressing thymosin beta-4 have a higher secondary to primary hair follicle ratio, suggesting potential for increased cashmere yield.

This review discusses the concept of drug repositioning and highlights fragmin and protamine as emerging biomaterials for tissue engineering and regenerative medicine, but it reports no new clinical results.

This study formulated a minoxidil-loaded submicron emulsion-based topical gel, which demonstrated effective in vitro release, ex vivo permeation, and stability, suggesting it may offer a targeted treatment approach for alopecia compared to traditional methods.

This review found that exposure to pollutants like PM, NOx, and PAHs is linked to various skin and hair disorders, indicating a need for cosmetics with natural adsorbents to reduce pollutant effects, achieving 30-55% removal efficiency.

This study found that maternal sub-maintenance nutrition reduced the density and branching ratio of secondary wool follicles in Merino sheep fetuses and identified genes potentially involved in these processes.

This study found that salivary testosterone levels were significantly lower in oligospermic and azoospermic men compared to normal men, suggesting its potential use in assessing male androgen status.

This study found that treatment with cyproterone acetate and ethinylestradiol in hirsute women reduced testosterone and androstenedione levels, decreased hair growth, and increased cortisol levels without changing catecholamine excretion.

Among obese women potentially eligible for combined oral contraceptives, this study observed a higher frequency of non-alcoholic fatty liver disease in those with polycystic ovary syndrome.

This review discusses the bioactive compounds and biological activities of Polygonum multiflorum Thunb. and highlights concerns about its hepatotoxicity, but reports no new clinical results.

In this study, a genetic analysis identified a pathogenic variant in the ALOXE3 gene associated with non-bullous congenital ichthyosiform erythroderma, and the patient's response to antifungal treatment highlights the risk of cutaneous fungal infections.

This study found that a 4:1 combination of Rhynchosia nulubilis and Polygonum multiflorum extracts significantly promoted the proliferation of human dermal papilla cells and alleviated testosterone-induced cytotoxicity, suggesting potential for treating hair loss and related disorders through a synergistic approach.

This review discusses the mechanisms and pathways of FGFR signalling and its roles in development, disorders, and therapeutic targeting, but reports no new clinical results.

A mutation in the KRT74 gene causes tightly curled hair.

This study found that the fermented black soybean product GR-SC65 reduced particulate matter-induced cell death and oxidative stress in A549 cells, suggesting potential as a therapeutic agent for lung injury prevention.

Some people have a genetic variation that makes them less effective at breaking down drugs.

In this study, inducing zinc deficiency in recently weaned female Tan rabbits led to reduced food consumption, weight loss, and reproductive issues, including inactive uterine and ovarian changes.

This review discusses the links between particulate matter exposure and skin diseases, highlighting oxidative stress and inflammation as key mechanisms; it reports no new clinical results.