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Dextran sulfate was found to be toxic and ineffective for treating HIV.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.

The right cells and signals can potentially lead to scarless wound healing, with a mix of natural and external wound healing controllers possibly being the best way to achieve this.

Dlx3 is essential for hair growth and regeneration.

Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Skin cells called dermal fibroblasts are important for skin growth, hair growth, and wound healing.

Frizzled receptors are essential for various body development processes and maintaining certain body functions.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Choosing the right model order in brain connectivity analysis can affect the detection of differences between healthy individuals and those with seasonal affective disorder.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Drug advertising has greatly increased, changing consumer behavior and raising concerns about its influence on healthcare and patient protection.

Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.

Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

A small group of slow-growing cells causes basal cell carcinoma to return after treatment.