research Simvastatin/Ezetimibe Therapy for Recalcitrant Alopecia Areata: An Open Prospective Study of 14 Patients
Simvastatin/ezetimibe may help some patients with severe alopecia areata regrow hair.
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research Hair Follicle Characteristics as Early Marker of Type 2 Diabetes
Hair characteristics might be early signs of Type 2 Diabetes and could help with early prevention.
research Serum Level of Macrophage Migration Inhibitory Factor in Egyptians With Alopecia Areata and Its Relation to the Clinical Severity of the Disease
Higher MIF levels in alopecia areata patients suggest it could be a treatment target and disease predictor.
research Protective Cardiovascular and Renal Actions of Vitamin D and Estrogen
Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.
research Laminin-511, Inducer of Hair Growth, Is Down-Regulated and Its Suppressor in Hair Growth, Laminin-332 Up-Regulated in Chemotherapy-Induced Alopecia
Chemotherapy-induced hair loss is partly due to decreased laminin-511 and increased laminin-332.
research Overexpression of spermidine/spermine N1-acetyltransferase under the control of mouse metallothionein I promoter in transgenic mice: evidence for a striking post-transcriptional regulation of transgene expression by a polyamine analogue
The study involved generating a transgenic mouse line overexpressing the SSAT gene under a mouse metallothionein I promoter, leading to significant changes in tissue polyamine pools and delayed permanent hair loss compared to previous models. The liver was notably affected, with drastic reductions in spermine and increases in putrescine. Despite high levels of SSAT mRNA, enzyme activity was only moderately elevated unless induced by ZnSO4 or the polyamine analogue DENSPM, which caused a massive increase in enzyme activity and depletion of spermidine and spermine pools. This treatment led to high mortality and liver damage, indicating that SSAT overexpression made the mice highly sensitive to polyamine analogues, suggesting a post-transcriptional regulation mechanism.
research Catamenial-Like Seizure Exacerbation in Mice with Targeted Ablation of Extrasynaptic δGABA-A Receptors in the Brain
Removing certain brain receptors in mice worsens seizure severity and response to treatment during hormone withdrawal.
research Interventional Studies for Polycystic Ovarian Syndrome in Children and Adolescents
Early treatment and lifestyle changes are important for managing PCOS in young people to prevent long-term health issues.
research Quorum Sensing and Other Collective Regenerative Behaviors in Organ Populations
Organs like hair follicles can renew themselves in complex ways, adapting to different needs and environments.
research Prevention of Unfavorable Effects of Cigarette Smoke on Flap Viability Using Botulinum Toxin in Random Pattern Flaps: An Experimental Study
Botulinum toxin may help reduce skin flap damage caused by cigarette smoke.
research Platycarya Strobilacea S. Et Z. Extract Has a High Antioxidant Capacity and Exhibits Hair Growth-Promoting Effects in Male C57BL/6 Mice
Platycarya strobilacea extract is a strong antioxidant that can grow hair better than minoxidil.
research Androgenetic Alopecia at Various Ages and Prostate Cancer Risk in an Equal-Access Multiethnic Case-Control Series of Veterans
Early balding, especially frontal, increases prostate cancer risk; more research needed.
research Trichomycosis (Trichobacteriosis) Axillaris
Shaving, erythromycin cream, and clotrimazole powder effectively treated the bad odor and rough hair.
research Acute Sensitivity of the Oral Mucosa to Oncogenic K-ras
Oncogenic K-ras causes rapid cancerous changes in the mouth's lining.
research Interleukin 6 and STAT3 Regulate p63 Isoform Expression in Keratinocytes During Regeneration
The conclusion is that the IL-6/STAT3 activation affects p63 expression in healing wounds, which may help in hair follicle regeneration.
research The Good, the Bad, and the Ugly Facets of Insulin Resistance
Insulin resistance is a complex condition that can lead to many diseases and has few treatment options.
research Use of an Alternating Inflatable Head Pad in Patients Undergoing Open Heart Surgery
An alternating inflatable head pad reduced pressure ulcers and hair loss in heart surgery patients.
research Localized Telogen Effluvium Following Hair Transplantation
Some people experienced temporary hair loss after hair transplant surgery but recovered fully within 10 months.
research Beyond Testosterone Cypionate: Evidence Behind the Use of Nandrolone in Male Health and Wellness
Nandrolone might increase muscle mass with fewer side effects than testosterone but could cause erectile dysfunction and needs more research.
research Recent Advances in Drug Design and Drug Discovery for Androgen-Dependent Diseases
New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
research Translational Positioning of Janus Kinase (JAK) Inhibitors in Alopecia Areata
JAK inhibitors may help treat Alopecia Areata but need careful monitoring due to side effects.
research Alternative Method for Creating Fine Hairs with Hair Removal Laser in Hair Transplantation for Hairline Correction
Using a hair removal laser can make hairs finer for better hairline correction in hair transplants, with most patients happy and few side effects.
research Protease Activity, Localization, and Inhibition in the Human Hair Follicle
The study suggests that a new protease inhibitor can make hair harder to pull out, potentially reducing hair loss.
research Haff Disease Associated With The Ingestion Of The Freshwater Fish Mylossoma Duriventre (Pacu-Manteiga)
Eating pacu-manteiga fish can cause Haff disease, leading to severe muscle damage.
research Ban Tu Wan Hepatotoxicity
Ban Tu Wan, a Chinese herbal supplement, can cause severe liver damage.
research A Pair of Transmembrane Receptors Essential for the Retention and Pigmentation of Hair
Bmpr2 and Acvr2a receptors are crucial for hair retention and color.
research Oral Testosterone With and Without Concomitant Inhibition of 5α-Reductase by Dutasteride in Hypogonadal Men for 28 Days
Taking oral testosterone with or without dutasteride increases testosterone levels and could be an effective treatment for low testosterone.
research Mechanism of Action of Bolandiol (19-Nortestosterone-3β,17β-Diol), a Unique Anabolic Steroid with Androgenic, Estrogenic, and Progestational Activities
Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.
research Australian Resources for Ethical Participatory Processes in Public Health Research
PRP injections may be an effective treatment for severe hair loss.
research Next-Generation Therapeutics for Skin Cancer: Nutraceuticals
Certain spices may help prevent and treat skin cancer, but more human trials are needed.