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Melatonin, usually known for sleep regulation, also has antioxidant properties that can protect skin, stimulate hair growth, and improve skin conditions, with topical application being more effective than oral use.

The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

The research found specific genes and pathways that control fur development and color in young American minks.

Targeting lipid metabolism can help treat advanced, resistant cancers.

New research shows that skin diversity is influenced by different types of dermal fibroblasts and their development, especially involving the Wnt/β-catenin pathway.

Hair is a complex organ, and understanding its detailed structure and growth phases is crucial for analyzing substances within it.

Hydrogels could lead to better treatments for wound healing without scars.

LEF1 is essential for the development of airway glands and is regulated by the Wnt/ß-catenin pathway.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

VEGFR-2 activation is likely involved in hair follicle growth, survival, and development.

MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.

Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.

Pseudopelade of Brocq is a unique hair loss condition, but its cause and development are still not fully understood.

The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.

Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.

Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

The document concludes that transplantology has evolved with improved techniques and materials, making transplants more successful and expanding the types of transplants possible.

Some cosmetic procedures show promise for treating hair loss, but more research is needed to confirm their safety and effectiveness.

Antioxidants may help improve mitochondrial health and could be used to treat diseases related to cell damage.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Platelet lysate is a promising, cost-effective option for regenerative medicine with potential clinical applications.

RADA16 is a promising material for tissue repair and regenerative medicine but needs improvement in strength and cost.

Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.

The document explains hair biology, the causes of hair loss, and reviews various hair loss treatments.

Changing light exposure can affect hair growth timing in goats, possibly due to a key gene, CSDC2.

Blocking the FGF5 gene in sheep leads to more fine wool and active hair follicles due to changes in certain cell signaling pathways.