research Unraveling the Link Between Ectodermal Disorders and Primary Immunodeficiencies
Skin abnormalities can indicate immunodeficiency due to shared origins with the immune system.
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research Mesenchymal Stem Cells With Modification of Junctional Adhesion Molecule A Induce Hair Formation
Modified stem cells that overexpress a specific protein can improve hair growth and reduce hair abnormalities in mice.
research Animal Models of Alopecia
The best animal model for studying male-pattern baldness is the stumptailed macaque, not rats or mice.
research Hereditary 1,25-Dihydroxyvitamin D-Resistant Rickets (HVDRR): Clinical Heterogeneity and Long-Term Efficacious Management of Eight Patients from Four Unrelated Arab Families with a Loss of Function VDR Mutation
Patients with the same genetic mutation for vitamin D-resistant rickets showed different symptoms but all improved with treatment except for hair loss.
research Genetic Correlation Analysis Does Not Associate Male Pattern Baldness With COVID-19
There's no significant genetic link between male pattern baldness and COVID-19.
research Future Directions in the Treatment of Vitiligo
New treatments for vitiligo may focus on protecting melanocyte stem cells from stress and targeting specific pathways involved in the condition.
research Flavonoids and Nod Factors: Importance in Legume-Microbe Interactions and Legume Improvement
Flavonoids and Nod factors are key for legume plant growth and could help in sustainable farming.
research Genetics of Polycystic Ovary Syndrome
PCOS has a strong genetic basis, but more research is needed to fully understand it.
research Androgen Excess: A Hallmark of Polycystic Ovary Syndrome
Excess androgens may cause PCOS, not just be a symptom.
research Vitamin D in Dermatology and Cosmetology
Vitamin D is crucial for skin health and managing skin diseases.
research Alymphoid Cystic Thymic Dysgenesis - FOXN1 Gene Mutation: A Rare Case Report of Two Siblings
Two siblings had a rare immune disorder caused by a FOXN1 gene mutation.
research Specific Ectodermal Enhancers Control the Expression of Hoxc Genes in Developing Mammalian Integuments
The HoxC gene cluster and its enhancers are essential for developing hair and nails in mammals.
research Perspectives of Alopecia Behind the Regulation of Foxn1 Gene Exposes the Human Nude Phenotype
The gene Foxn1 is important for hair growth, and understanding it may lead to new alopecia treatments.
research Ligand-Independent Actions of Vitamin D Receptor
The vitamin D receptor helps maintain hair and bone health even without binding vitamin D.
research Does the Corticotropin-Releasing Hormone System Play a Role in the Pathogenesis of Lichen Planus?
The CRH/CRH-R1 system might be involved in causing lichen planus.
research Darwinian Health and Other Contradictions
The document concludes that understanding health requires considering evolutionary perspectives on reproductive fitness, and recognizing the complexity of factors like diet, testosterone, and sexual orientation.
research The Comparison of Blood Lipid Profile in Patients with and Without Androgenetic Alopecia
There's no significant link between blood fat levels and male pattern baldness.
research Effect of N-Acetylcysteine on Hair Follicle Changes in Mouse Model of Cyclophosphamide-Induced Alopecia: Histological and Biochemical Study
N-acetylcysteine may prevent hair loss caused by chemotherapy.
research The Skin as an Endocrine Organ
The skin produces and processes hormones, affecting both local and overall body functions.
research Human Clinical Phenotype Associated With FOXN1 Mutations
FOXN1 mutations cause severe immunodeficiency, hair loss, nail issues, and thymus defects.
research Retinoic Acid Drives Hair Follicle Stem Cell Activation via Wnt/Beta-Catenin Signalling in Androgenetic Alopecia
Retinoic acid helps activate hair growth in people with common hair loss by working on a specific cell growth pathway.
research Novel Insights Into the Molecular Mechanisms Underlying Generalized Glucocorticoid Resistance and Hypersensitivity Syndromes
Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.
research The Human Skin as a Hormone Target and an Endocrine Gland
Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.
research Corticotropin-Releasing Hormone and the Skin
CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.
research Hair Growth Induction by the Tellurium Immunomodulator AS101: Association with Delayed Terminal Differentiation of Follicular Keratinocytes and Ras-Dependent Up-Regulation of KGF Expression
The substance AS101 can help hair grow by slowing down hair cell aging and boosting a hair growth protein.
research Recent Advances in the Molecular Mechanisms Causing Primary Generalized Glucocorticoid Resistance
Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.
research Suppression of Vitamin D Receptor and Induction of Retinoid X Receptor Alpha Expression During Squamous Differentiation of Cultured Keratinocytes
As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.
research Vitamin D and Alopecia Areata: Possible Roles in Pathogenesis and Potential Implications for Therapy
Vitamin D might be involved in the development of alopecia areata and could help in its treatment.
research The Tale of Stress: An Exploratory Analysis of Cortisol Levels in the Tail Hair of Captive Asian Elephants
Elephant tail-hair can show past stress levels, matching times when stressful events happened.
research Does Androgenic Alopecia Aggravate the Risk of Prostate Cancer? Evidence from Mendelian Randomization
Male pattern baldness does not cause an increased risk of prostate cancer.