research Mouse Models for the Study of Human Hair Loss
Mice are useful for researching human hair loss and testing treatments, despite some differences between species.
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research Herbal Nano-Formulations for Topical Delivery
Herbal nano-formulations show potential for effective skin delivery but need more research.
research Macrophages Promote Wound-Induced Hair Follicle Regeneration in a CX3CR1- and TGF-β1-Dependent Manner
Macrophages help hair growth after injury through CX3CR1 and TGF-β1.
research Aromatase Deficiency in a Male Patient: Case Report and Literature Review
A male with aromatase deficiency improved bone health with estradiol treatment.
research Endogenous Human Skin Equivalent Promotes In Vitro Morphogenesis of Follicle-Like Structures
Endo-HSE helps grow hair-like structures from human skin cells in the lab.
research Mind the Gender Gap: Does Prolactin Exert Gender and Site-Specific Effects on the Human Hair Follicle?
Prolactin may affect hair growth differently based on gender and scalp area.
research Syphilis: The Great Imitator
Syphilis has a wide range of symptoms that can look like other diseases, and if not treated, it can progress to a more serious stage, especially in HIV-positive patients.
research A Review of the FAERS Data on 5-Alpha Reductase Inhibitors: Implications for Postfinasteride Syndrome
The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.
research Roxithromycin-Loaded Lipid Nanoparticles for Follicular Targeting
Tiny particles carrying roxithromycin can effectively target and deliver the drug to hair follicles without irritation.
research Neuroactive Gonadal Drugs for Neuroprotection in Male and Female Models of Parkinson's Disease
Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.
research Evaluation of Platelet-Rich Plasma as a Treatment for Androgenetic Alopecia: A Randomized Controlled Trial
PRP treatment improves hair density and thickness for alopecia, but needs more research.
research Transdermal Finasteride Delivery via Powder-Carrying Microneedles with a Diffusion Enhancer to Treat Androgenetic Alopecia
Microneedles with enhancer effectively promote hair growth and increase hair density.
research Androgenetic Alopecia in COVID-19: Comparison to Age-Matched Epidemiologic Studies and Hospital Outcomes With or Without the Gabrin Sign
AGA linked to worse COVID-19 outcomes in men.
research Formulation and Optimization of Transfersome Containing Minoxidil and Caffeine
Minoxidil and caffeine in transfersomes improve hair growth treatment.
research In Vitro and In Vivo Skin Distribution of 5α-Reductase Inhibitors Loaded Into Liquid Crystalline Nanoparticles
Chitosan-coated nanoparticles improve skin delivery of hair loss treatments with fewer side effects.
research STAT5 Activation in the Dermal Papilla Is Important for Hair Follicle Growth Phase Induction
STAT5 activation is crucial for starting the hair growth phase.
research Lack of Collagen VI Promotes Wound-Induced Hair Growth
Mice without collagen VI have slower hair growth normally but faster regrowth after injury.
research Male Breast Cancer and 5α-Reductase Inhibitors Finasteride and Dutasteride
Using finasteride or dutasteride does not increase the risk of male breast cancer.
research Fibrosing Alopecia in a Pattern Distribution
Fibrosing alopecia in a pattern distribution is a hair loss condition often confused with other types, requiring early treatment but usually not resulting in significant hair regrowth.
research Hair Growth-Promoting Activities of Chitosan and Surface-Deacetylated Chitin Nanofibers
Chitosan and surface-deacetylated chitin nanofibers may help treat hair loss.
research Acanthosis Nigricans and the Metabolic Syndrome
Acanthosis nigricans is a skin condition that may indicate a higher risk for insulin resistance and type 2 diabetes, and more research is needed to understand and treat it.
research Alopecia and the Metabolic Syndrome
Men with common hair loss may have a higher risk of heart disease and diabetes, and should be checked for these conditions.
research Characterization of Cell Cycle Arrest and Terminal Differentiation in a Maximally Proliferative Human Epithelial Tissue: Lessons from the Human Hair Follicle Matrix
CIP/KIP proteins help stop cell division and support hair growth.
research Transdermal Film-Loaded Finasteride Microplates to Enhance Drug Skin Permeation: Two-Step Optimization Study
Optimized film improves finasteride skin absorption and treatment efficiency.
research UHPLC/Q-TOFMS-Based Plasma Metabolomics of Polycystic Ovary Syndrome Patients With and Without Insulin Resistance
The research found different metabolism changes in PCOS patients and suggested new potential markers for diagnosing PCOS with or without insulin resistance.
research Treatment of Alopecia Areata With Steroid Solution
The steroid solution can regrow hair but often causes skin issues and doesn't work long-term.
research Male Balding Is a Major Risk Factor for Severe COVID-19
Men with severe balding have a higher risk of getting very sick from COVID-19.
research Incidence of Type 2 Diabetes Mellitus in Men Receiving Steroid 5α-Reductase Inhibitors: Population-Based Cohort Study
Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.
research Enzyme Replacement Therapy Ameliorates Multiple Symptoms of Murine Homocystinuria
Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.
research Re-Evaluating Cyclosporine A as a Hair Growth–Promoting Agent in Human Scalp Hair Follicles
Cyclosporine A promotes hair growth and prolongs the active growth phase in human hair follicles, but may work differently than in rodents.