58 citations
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December 2018 in “Nature Communications” This study found that male pattern baldness in European males is strongly heritable and associated with genetic markers linked to earlier puberty, bone density, and pancreatic function.
43 citations
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December 2020 in “PLOS Genetics” This study used a new statistical approach, PLACO, to identify several novel shared genetic regions associated with both Type 2 Diabetes and Prostate Cancer in two large GWAS datasets.
30 citations
,
February 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that the orphan protein Plet-1 is expressed in specific keratinocytes of mouse hair follicles and may regulate keratinocyte interactions with inert tissues by affecting migration and adhesion.
29 citations
,
June 2020 in “International Journal of Molecular Sciences” This review discusses the role of Notch signaling in skin diseases such as Hidradenitis Suppurativa and Psoriasis, but reports no new clinical results.
18 citations
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January 2018 in “BMC dermatology” This paper describes a case of epidermolysis bullosa simplex with muscular dystrophy associated with a novel PLEC mutation and diffuse alopecia, highlighting a potential genetic link that remains uncertain.
16 citations
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May 1982 in “Postgraduate Medical Journal” Minoxidil can cause pericardial and pleural effusions with high protein content.
9 citations
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January 1975 in “PubMed” In this study, researchers using a mouse model found that the hairlessness in nude mice is likely due to a shared defect in the thymus and skin, not thymic dysgenesis alone.
7 citations
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December 2021 in “Curēus” This review outlines the diverse clinical presentations of cutaneous metastases in breast cancer patients and emphasizes the importance of biopsy for accurate diagnosis, but reports no new results.
7 citations
,
June 2021 in “Cureus” This case report discusses minoxidil-induced anasarca as a potential side effect in patients using minoxidil for hypertension, emphasizing the importance of recognizing it for early diagnosis and management.
4 citations
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January 2011 This study found that Pleuropterus cilinervis extracts and animal milk fermented with Lactobacillus rhamnosus promoted hair growth in mice, suggesting potential applications in hair loss treatments.
1 citations
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October 2023 in “Journal of clinical psychopharmacology” In this case report, a young male developed bilateral pleural effusion and persistent fever after starting divalproex sodium for bipolar disorder, which improved upon discontinuation of the drug, suggesting a possible link between divalproex sodium and pleural effusion.
1 citations
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June 2022 in “Current drug safety” This case report highlights that a patient developed pleural effusion due to unintentional oral use of topical minoxidil, despite not having chronic kidney disease.
1 citations
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June 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This symposium discussed recent advances in understanding skin as a sensory organ, emphasizing the interactions between itch, pain, and touch pathways and highlighting potential therapeutic targets.
July 2026 in “Current Issues in Molecular Biology” This study found that Plerixafor, a CXCR4 antagonist, promotes melanogenesis in melanocytes by increasing MITF and tyrosinase expression and enhancing melanocyte migration, and it effectively restores pigmentation in a mouse depigmentation model without toxicity, highlighting its potential for treating pigmentary disorders.
March 2026 in “Preprints.org” In this study, plerixafor was found to enhance melanogenesis and promote repigmentation by engaging a β-arrestin–β-catenin–MITF signaling axis in melanocytes, and showed effectiveness in restoring depigmentation in a murine model without causing systemic toxicity.
December 2025 in “Journal of Holistic Integrative Pharmacy” This review discusses the traditional use and potential application of Polygoni multiflori radix for androgenetic alopecia treatment, emphasizing its promising safety profile but reporting no new clinical results.
July 2024 in “Russian Journal of Child Neurology” This study observed that among children with neurofibromatosis type 1 in Russia, selumetinib treatment led to a partial reduction in plexiform neurofibroma volume in 65% of cases, with 56% showing a long-term response without surgery; common side effects included skin rash and hair issues.
This case report highlights a rare instance of minoxidil-induced pleuro-pericardial effusion with tamponade in a patient with end-stage renal disease on hemodialysis, which improved following pericardiocentesis and discontinuation of the drug.
April 2023 in “Journal of Investigative Dermatology” This study found that alopecia areata patients have higher odds of certain comorbidities like ulcerative colitis and vitiligo, while showing lower odds for conditions like hypertension and type 2 diabetes compared to healthy controls.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” In this case study, a 26-year-old female with PLEC mutations and features of muscular dystrophy and myasthenia gravis showed significant improvement in symptoms following steroid treatment.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This case study reports that a 26-year-old woman with epidermolysis bullosa prurogompsa also presented with unique findings of co-existing muscular dystrophy and immune-based myasthenia gravis, with significant improvement following steroid treatment.
September 2016 in “Journal of Dermatological Science” This study found that P. cornucopiae extract showed antioxidant and protective effects on human skin fibroblasts, suggesting its potential as an antiaging agent by preventing oxidative stress-induced collagen breakdown.
137 citations
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May 1984 in “Journal of Investigative Dermatology” Minoxidil increases blood flow in balding scalps, possibly reversing hair loss.
21 citations
,
January 2020 in “Pharmaceutical Biology” In this study, Salvia plebeia extract promoted hair growth by enhancing proliferation and anti-apoptotic effects in human dermal papilla cells and increased hair growth in treated mice.
6 citations
,
June 2024 in “Biofabrication” This study used digital-light-processing bioprinting to create a 3D skin-on-a-chip model with a miniaturized vascular network to closely study immune cell interactions similar to real human skin, demonstrating the potential to analyze immune-T cell trafficking influenced by skin signals.
A woman's use of minoxidil for hair loss caused fluid buildup in her chest, which went away when she stopped using the product.
August 2025 in “Ophthalmic Plastic and Reconstructive Surgery” In this case report, a 4-year-old with neurofibromatosis type 1 experienced significant reduction in an inoperable periorbital plexiform neurofibroma and visual improvement following treatment with selumetinib.
December 2021 in “Black sea journal of health science” This case report describes a 31-year-old male who developed eosinophilic pleuropericardial effusion potentially linked to long-term valproic acid use, which resolved after adjusting his medication.
June 2008 in “British Journal of Dermatology” This article summarizes the main plenary sessions of the 88th Annual Meeting of the British Association of Dermatologists and reports no new clinical findings.
July 2004 in “British Journal of Dermatology” This paper summarizes the main findings presented in the plenary sessions of the British Journal of Dermatology, July 2004 issue, and provides no new research results.