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    Glossary Platelet-Derived Growth Factor

    protein that stimulates cell growth and tissue repair

    Platelet-Derived Growth Factor (PDGF) is a protein that plays a crucial role in wound healing and the growth of blood vessels. It is released by platelets in the blood and stimulates cells to divide and grow, which is essential for tissue repair and regeneration. PDGF is also involved in various cellular processes, including the development of hair follicles, making it relevant in treatments for conditions like alopecia.

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    1. Platelet-derived growth factor signaling modulates adult hair follicle dermal stem cell maintenance and self-renewal npj Regenerative Medicine · 2017 · 37 citations
    2. Intraovarian vascular enhancement via stromal injection of platelet-derived growth factors: Exploring subsequent oocyte chromosomal status and in vitro fertilization outcomes 2020 · 25 citations
    3. Human hair follicle stem cell differentiation into contractile smooth muscle cells is induced by transforming growth factor-β1 and platelet-derived growth factor BB Molecular Medicine Reports · 2013 · 19 citations
    4. A New Advance in Baldness Surgery Using Platelet-Derived Growth Factor Hair transplant forum international · 2005 · 17 citations
    5. Platelet-derived growth factor regulates the proliferation and differentiation of human melanocytes in a differentiation-stage-specific manner Journal of Dermatological Science · 2016 · 10 citations
    6. Expression of CD117 and platelet-derived growth factor receptor α in patients with alopecia areata Indian journal of dermatology, venereology, and leprology · 2020 · 1 citations
    7. Signaling by the Platelet-Derived Growth Factor Receptor Family 2009
    8. The effect of platelet-derived growth factor-aa (PDGFA) conjugated with low-molecular-weight protamine (LMWP) on hair loss improvement effect Biochemical and Biophysical Research Communications · 2024
    9. Effect of 10% calcium gluconate on the activation of platelet-rich plasma obtained at different centrifugation conditions on the expression of platelet derived growth factor-BB (PDGF-BB) Universidad Peruana Cayetano Heredia Institutional Repository · 2024
    10. Evaluation of intralesional injection of platelet derived growth factors PDGF ma in patients with Peyronie's disease 2025
    11. In vitro expansion of human mesenchymal stem cells and hepatocytes using purified platelet derived growth factors, a potential therapeutic modality for liver fibrosis Egyptian journal of Immunology · 2023
    12. 432 Patient and device generated variability in platelet-derived growth factors during platelet-rich plasma therapy for hair loss Journal of Investigative Dermatology · 2019
    13. In the Absence of Streptomycin, Minoxidil Potentiates the Mitogenic Effects of Fetal Calf Serum, Insulin-Like Growth Factor 1, and Platelet-Derived Growth Factor on NIH 3T3 Fibroblasts in a K + Channel-Dependent Fashion Journal of Investigative Dermatology · 1996 · 32 citations
    14. 878 Individual variation in balance between platelet-secreted growth factors causing contradictory effects on hair follicle could potentially impact response to PRP therapy in patients with scalp hair loss Journal of Investigative Dermatology · 2018 · 1 citations
    15. Enriched-GF: A Reproducible High-Yield Autologous Blood-Derived Growth Factor Method for Regenerative Medicine bioRxiv (Cold Spring Harbor Laboratory) · 2026
    16. Platelet-derived extracellular vesicles promote hair follicle growth through β-catenin signaling pathway Platelets · 2025
    17. The Impact of Growth Factors in Platelet‐Rich Plasma Combination Therapy for Androgenic Alopecia Dermatologic Therapy · 2024
    18. Progenic hair regrowth treatment- The use of platelet-released growth factors for treating androgenetic alopecia (AGA) by activating hair follicle stem cells Journal of clinical & experimental dermatology research · 2014
    19. A pilot study on relationship between quantity of growth factors and cytokines to blood groups in umbilical cord blood-derived PRP Journal of 108 - Clinical Medicine and Phamarcy · 2025
    20. Dual growth factor releasing multi-functional nanofibers for wound healing Acta Biomaterialia · 2013 · 355 citations
    21. GROWTH FACTORS IN HAIR ORGAN DEVELOPMENT AND THE HAIR GROWTH CYCLE Dermatologic Clinics · 1996 · 90 citations
    22. Generation of trichogenic adipose-derived stem cells by expression of three factors Journal of Dermatological Science · 2018 · 12 citations
    23. An Overview of Growth Factors as the Potential Link between Psoriasis and Metabolic Syndrome Journal of Clinical Medicine · 2023 · 6 citations
    24. Anti-oxidant Efficacy and Effects on Expression of Growth Factors in Human Hair Follicle Dermal Papilla Cells of Rosa multiflora Root Extracts Asian journal of beauty & cosmetology · 2017 · 6 citations
    25. Sodium pentaborate pentahydrate promotes hair growth through the Wnt/β-catenin pathway and growth factors Journal of trace elements in medicine and biology · 2022 · 2 citations
    26. Role of Growth Factors-Rich Plasma, Gel and Membrane in Dermal Wound Healing and Injured Tissue Restoration and Regeneration European journal of medical and health sciences · 2021 · 1 citations
    27. Hypoxia-Induced Mesenchymal Stem Cell-Derived Exosome Enhance TGF-β, PDGF, and Hair Growth in Alopecia-Like Rat Models Biosaintifika Journal of Biology & Biology Education · 2026
    28. Subcutaneous injection of conditioned medium from photobiomodulation-treated adipose-derived stromal cells promotes hair growth and angiogenesis in mice Archives of Dermatological Research · 2025
    29. Concentrated growth factor therapy as cosmetic treatment in discoid lupus erythematosus Journal of dermatology · 2024
    30. Garlic Exosomes Promote Hair Growth Through the Wnt/β-catenin Pathway and Growth Factors Cureus · 2023