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    Glossary Platelet-Derived Growth Factor Receptor

    cell surface receptor that binds to growth factors for cell processes

    Platelet-Derived Growth Factor Receptor (PDGFR) is a cell surface receptor that binds to platelet-derived growth factors (PDGFs). When PDGFs attach to PDGFR, it triggers a series of cellular processes, including cell growth, division, and survival. This receptor plays a crucial role in wound healing and the development of blood vessels, and its malfunction can be associated with various diseases, including cancers and fibrotic conditions.

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    1. Expression of CD117 and platelet-derived growth factor receptor α in patients with alopecia areata Indian journal of dermatology, venereology, and leprology · 2020 · 1 citations
    2. Signaling by the Platelet-Derived Growth Factor Receptor Family 2009
    3. GROWTH FACTORS IN HAIR ORGAN DEVELOPMENT AND THE HAIR GROWTH CYCLE Dermatologic Clinics · 1996 · 90 citations
    4. Regulation of PDGF and PDGF receptor in cultured dermal papilla cells and follicular keratinocytes of the human hair follicle Experimental Dermatology · 2003 · 55 citations
    5. Tyrosine Kinase Inhibitors – A Review on Pharmacology, Metabolism and Side Effects Current drug metabolism · 2009 · 508 citations
    6. Advances in the Management of Cutaneous Toxicities of Targeted Therapies Seminars in Oncology · 2012 · 42 citations
    7. Hair graying and loss induced by imatinib mesylate The Journal of Dermatology · 2013 · 7 citations
    8. Rebamipide Induces Hair Regeneration Through EP4-Driven Lipid Metabolism Remodeling International Journal of Molecular Sciences · 2025
    9. Expression Profiles of Tyrosine Kinases in Cultured Follicular Papilla Cells Versus Dermal Fibroblasts Journal of Investigative Dermatology · 2004 · 11 citations
    10. Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis Genes & Development · 2008 · 102 citations
    11. PDGFA regulation of dermal adipocyte stem cells Stem cell investigation · 2017 · 3 citations
    12. 174 Dermis-hair follicle communication: Extracellular microvesicles signaling for hair regeneration Journal of Investigative Dermatology · 2020
    13. Anti-PDGF receptor β antibody-conjugated squarticles loaded with minoxidil for alopecia treatment by targeting hair follicles and dermal papilla cells Nanomedicine: Nanotechnology, Biology and Medicine · 2015 · 17 citations
    14. The pivotal role of PDGF and its receptor isoforms in adipose-derived stem cells. PubMed · 2015 · 23 citations
    15. Platelet-derived growth factor signaling modulates adult hair follicle dermal stem cell maintenance and self-renewal npj Regenerative Medicine · 2017 · 37 citations
    16. In vitro expansion of human mesenchymal stem cells and hepatocytes using purified platelet derived growth factors, a potential therapeutic modality for liver fibrosis Egyptian journal of Immunology · 2023
    17. The effect of platelet-derived growth factor-aa (PDGFA) conjugated with low-molecular-weight protamine (LMWP) on hair loss improvement effect Biochemical and Biophysical Research Communications · 2024
    18. Human hair follicle stem cell differentiation into contractile smooth muscle cells is induced by transforming growth factor-β1 and platelet-derived growth factor BB Molecular Medicine Reports · 2013 · 19 citations
    19. Hair growth stimulated by conditioned medium of adipose-derived stem cells is enhanced by hypoxia: evidence of increased growth factor secretion Biomedical research · 2010 · 134 citations
    20. Platelet factor 4 inhibits human hair follicle growth and promotes androgen receptor expression in human dermal papilla cells PeerJ · 2020 · 4 citations
    21. Progenic hair regrowth treatment- The use of platelet-released growth factors for treating androgenetic alopecia (AGA) by activating hair follicle stem cells Journal of clinical & experimental dermatology research · 2014
    22. Platelet-derived extracellular vesicles promote hair follicle growth through β-catenin signaling pathway Platelets · 2025
    23. Investigation of the effect of anticoagulants on platelet recovery, enrichment factor, PDGF, TGF-β1 and optimal dose in the preparation of platelet-rich plasma Research Square (Research Square) · 2023
    24. Versatility of autologous growth factor concentrate therapy in early-stage androgenetic alopecia: A case report Asian Journal of Oral Health and Allied Sciences · 2025
    25. Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth-Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development Cells · 2019 · 136 citations
    26. Sodium pentaborate pentahydrate promotes hair growth through the Wnt/β-catenin pathway and growth factors Journal of trace elements in medicine and biology · 2022 · 2 citations
    27. An Overview of Growth Factors as the Potential Link between Psoriasis and Metabolic Syndrome Journal of Clinical Medicine · 2023 · 6 citations
    28. Novel effect of sildenafil on hair growth Biochemical and Biophysical Research Communications · 2018 · 16 citations
    29. Role of Growth Factors-Rich Plasma, Gel and Membrane in Dermal Wound Healing and Injured Tissue Restoration and Regeneration European journal of medical and health sciences · 2021 · 1 citations
    30. The Use of Adipose-Derived Stem Cells in Selected Skin Diseases (Vitiligo, Alopecia, and Nonhealing Wounds) Stem Cells International · 2017 · 19 citations