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    Glossary Platelet-Derived Growth Factor BB

    protein that stimulates cell growth and tissue repair

    Platelet-Derived Growth Factor BB (PDGF-BB) is a protein that plays a crucial role in cell growth, healing, and the formation of blood vessels. It is one of the isoforms of PDGF and is particularly important in wound healing and tissue repair, as it stimulates the proliferation and migration of cells such as fibroblasts and smooth muscle cells.

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    1. Human hair follicle stem cell differentiation into contractile smooth muscle cells is induced by transforming growth factor-β1 and platelet-derived growth factor BB Molecular Medicine Reports · 2013 · 19 citations
    2. Effect of 10% calcium gluconate on the activation of platelet-rich plasma obtained at different centrifugation conditions on the expression of platelet derived growth factor-BB (PDGF-BB) Universidad Peruana Cayetano Heredia Institutional Repository · 2024
    3. Platelet-derived growth factor regulates the proliferation and differentiation of human melanocytes in a differentiation-stage-specific manner Journal of Dermatological Science · 2016 · 10 citations
    4. Platelet-derived growth factor signaling modulates adult hair follicle dermal stem cell maintenance and self-renewal npj Regenerative Medicine · 2017 · 37 citations
    5. Signaling by the Platelet-Derived Growth Factor Receptor Family 2009
    6. The Impact of Growth Factors in Platelet‐Rich Plasma Combination Therapy for Androgenic Alopecia Dermatologic Therapy · 2024
    7. Platelet-derived extracellular vesicles promote hair follicle growth through β-catenin signaling pathway Platelets · 2025
    8. A pilot study on relationship between quantity of growth factors and cytokines to blood groups in umbilical cord blood-derived PRP Journal of 108 - Clinical Medicine and Phamarcy · 2025
    9. Dual growth factor releasing multi-functional nanofibers for wound healing Acta Biomaterialia · 2013 · 355 citations
    10. An Overview of Growth Factors as the Potential Link between Psoriasis and Metabolic Syndrome Journal of Clinical Medicine · 2023 · 6 citations
    11. Industrial Mass Production of Platelet Dry Powder Applied sciences · 2023
    12. 878 Individual variation in balance between platelet-secreted growth factors causing contradictory effects on hair follicle could potentially impact response to PRP therapy in patients with scalp hair loss Journal of Investigative Dermatology · 2018 · 1 citations
    13. 26SCS-Loaded SilMA/Col Composite Sponge with Well-Arranged Layers Promotes Angiogenesis-Based Diabetic Wound Repair by Mediating Macrophage Inflammatory Response 2024
    14. PDGF isoforms induce and maintain anagen phase of murine hair follicles Journal of Dermatological Science · 2006 · 136 citations
    15. The effect of platelet-derived growth factor-aa (PDGFA) conjugated with low-molecular-weight protamine (LMWP) on hair loss improvement effect Biochemical and Biophysical Research Communications · 2024
    16. Novel effect of sildenafil on hair growth Biochemical and Biophysical Research Communications · 2018 · 16 citations
    17. Expression of CD117 and platelet-derived growth factor receptor α in patients with alopecia areata Indian journal of dermatology, venereology, and leprology · 2020 · 1 citations
    18. Enriched-GF: A Reproducible High-Yield Autologous Blood-Derived Growth Factor Method for Regenerative Medicine bioRxiv (Cold Spring Harbor Laboratory) · 2026
    19. Progenic hair regrowth treatment- The use of platelet-released growth factors for treating androgenetic alopecia (AGA) by activating hair follicle stem cells Journal of clinical & experimental dermatology research · 2014
    20. Investigation of the effect of anticoagulants on platelet recovery, enrichment factor, PDGF, TGF-β1 and optimal dose in the preparation of platelet-rich plasma Research Square (Research Square) · 2023
    21. Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth-Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development Cells · 2019 · 136 citations
    22. Alopecia and platelet-derived therapies Stem cell investigation · 2017 · 23 citations
    23. Role of Growth Factors-Rich Plasma, Gel and Membrane in Dermal Wound Healing and Injured Tissue Restoration and Regeneration European journal of medical and health sciences · 2021 · 1 citations
    24. Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis Genes & Development · 2008 · 102 citations
    25. Platelet-Rich Plasma and Micrografts Enriched with Autologous Human Follicle Mesenchymal Stem Cells Improve Hair Re-Growth in Androgenetic Alopecia. Biomolecular Pathway Analysis and Clinical Evaluation Biomedicines · 2019 · 69 citations
    26. Fibroblasts: Origins, definitions, and functions in health and disease Cell · 2021 · 488 citations
    27. PDGFA in Cashmere Goat: A Motivation for the Hair Follicle Stem Cells to Activate Animals · 2019 · 19 citations
    28. Optimal stimulation toward the dermal papilla lineage can be promoted by combined use of osteogenic and adipogenic inducers FEBS open bio · 2019 · 2 citations
    29. Referee report. For: Molecular mediators involved in skin healing: a narrative review [version 1; peer review: 1 approved with reservations] Faculty of 1000 Research Ltd · 2022
    30. Expression Profiles of Tyrosine Kinases in Cultured Follicular Papilla Cells Versus Dermal Fibroblasts Journal of Investigative Dermatology · 2004 · 11 citations