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    Did you mean Platelet-Derived Growth Factor AA?
    Glossary Platelet-Derived Growth Factor AA

    stimulates cell growth and tissue repair, including hair follicles

    Platelet-Derived Growth Factor AA (PDGF-AA) is a protein that plays a crucial role in cell growth, healing, and development. It is one of the isoforms of PDGF, which are important for stimulating the proliferation and differentiation of cells, particularly in the context of wound healing and tissue repair. In the realm of hair biology, PDGF-AA can influence hair follicle development and regeneration, making it a potential target for treatments related to hair loss and alopecia.

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    1. In the Absence of Streptomycin, Minoxidil Potentiates the Mitogenic Effects of Fetal Calf Serum, Insulin-Like Growth Factor 1, and Platelet-Derived Growth Factor on NIH 3T3 Fibroblasts in a K + Channel-Dependent Fashion Journal of Investigative Dermatology · 1996 · 32 citations
    2. Signaling by the Platelet-Derived Growth Factor Receptor Family 2009
    3. Enriched-GF: A Reproducible High-Yield Autologous Blood-Derived Growth Factor Method for Regenerative Medicine bioRxiv (Cold Spring Harbor Laboratory) · 2026
    4. The Combined Use of Platelet-Rich Plasma and Adipose-Derived Mesenchymal Stem Cells Promotes Healing. A Review of Experimental Models and Future Perspectives Biomolecules · 2021 · 4 citations
    5. Effect of IGF-I on Hair Growth Is Related to the Anti-Apoptotic Effect of IGF-I and Up-Regulation of PDGF-A and PDGF-B Annals of Dermatology · 2012 · 72 citations
    6. A Multi-Donor Ex Vivo Platelet Activation and Growth Factor Release Study Using Electric Pulses With Durations Up to 100 Microseconds IEEE Access · 2021 · 5 citations
    7. A pilot study on relationship between quantity of growth factors and cytokines to blood groups in umbilical cord blood-derived PRP Journal of 108 - Clinical Medicine and Phamarcy · 2025
    8. Concentrated Conditioned Medium-Loaded Silk Nanofiber Hydrogels with Sustained Release of Bioactive Factors To Improve Skin Regeneration ACS Applied Bio Materials · 2019 · 5 citations
    9. PDGFA in Cashmere Goat: A Motivation for the Hair Follicle Stem Cells to Activate Animals · 2019 · 19 citations
    10. Progenic hair regrowth treatment- The use of platelet-released growth factors for treating androgenetic alopecia (AGA) by activating hair follicle stem cells Journal of clinical & experimental dermatology research · 2014
    11. Platelet-Rich Plasma (PRP) and Adipose-Derived Stem Cell (ADSC) Therapy in the Treatment of Genital Lichen Sclerosus: A Comprehensive Review International Journal of Molecular Sciences · 2023 · 24 citations
    12. Advances in the Management of Cutaneous Toxicities of Targeted Therapies Seminars in Oncology · 2012 · 42 citations
    13. A Potential Differentiation of Adipose and Hair Follicle-derived Mesenchymal Stem Cells to Generate Neurons Induced with EGF, FGF, PDGF and Forskolin Research Journal of Pharmacy and Technology · 2020 · 14 citations
    14. Generation of trichogenic adipose-derived stem cells by expression of three factors Journal of Dermatological Science · 2018 · 12 citations
    15. An Overview of Growth Factors as the Potential Link between Psoriasis and Metabolic Syndrome Journal of Clinical Medicine · 2023 · 6 citations
    16. Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth-Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development Cells · 2019 · 136 citations
    17. GROWTH FACTORS IN HAIR ORGAN DEVELOPMENT AND THE HAIR GROWTH CYCLE Dermatologic Clinics · 1996 · 90 citations
    18. Effects of platelet-rich plasma on in vitro hair follicle germ preparation for hair regenerative medicine Journal of Bioscience and Bioengineering · 2020 · 10 citations
    19. Sodium pentaborate pentahydrate promotes hair growth through the Wnt/β-catenin pathway and growth factors Journal of trace elements in medicine and biology · 2022 · 2 citations
    20. Role of Platelet Rich Fibrin (PRF) in Treatment of Post Acne Scars: Review Article The Egyptian Journal of Hospital Medicine · 2022
    21. Fibroblasts: Origins, definitions, and functions in health and disease Cell · 2021 · 488 citations
    22. Hypoxia Treatment of Adipose Mesenchymal Stem Cells Promotes the Growth of Dermal Papilla Cells via HIF-1α and ERK1/2 Signaling Pathways International Journal of Molecular Sciences · 2023 · 1 citations
    23. The Use of Adipose-Derived Stem Cells in Selected Skin Diseases (Vitiligo, Alopecia, and Nonhealing Wounds) Stem Cells International · 2017 · 19 citations
    24. Advancing fat graft survival: from adipose-derived stem cell mechanisms to next-generation regenerative strategies Frontiers in Cell and Developmental Biology · 2026
    25. Novel effect of sildenafil on hair growth Biochemical and Biophysical Research Communications · 2018 · 16 citations
    26. Hair, Cutaneous Homeostasis and Stem Cell Functions Journal of Investigative Dermatology · 2014
    27. Chemically induced transformation of human dermal fibroblasts to hair‐inducing dermal papilla‐like cells Cell Proliferation · 2019 · 8 citations
    28. Hair graying and loss induced by imatinib mesylate The Journal of Dermatology · 2013 · 7 citations
    29. Autologous adipose derived stem cell versusplatelet rich plasma injection in the treatment of androgentic alopecia: Efficacy, side effects and safety Cytotherapy · 2018
    30. Evaluation of intralesional injection of platelet derived growth factors PDGF ma in patients with Peyronie's disease 2025